نتایج جستجو برای: stag3
تعداد نتایج: 40 فیلتر نتایج به سال:
We analyzed transmission of a ring minichromosome (MC) through mouse spermatogenesis as a monosome and in the presence of a homologue. Mice, either monosomic or disomic for the MC, produced MC+ offspring. In the monosomic condition, most univalents underwent self-synapsis as indicated by STAG3, SCP3, and SCP1 deposition. Fluorescent in situ hybridization and three-dimensional fluorescence micro...
Marsupial sex chromosomes break the rule that recombination during first meiotic prophase is necessary to ensure reductional segregation during first meiotic division. It is widely accepted that in marsupials X and Y chromosomes do not share homologous regions, and during male first meiotic prophase the synaptonemal complex is absent between them. Although these sex chromosomes do not recombine...
Human papilloma virus (HPV)-associated head and neck squamous cell carcinoma (HNSCC) has a better prognosis than it's HPV negative (HPV(-)) counterpart. This may be due to the higher numbers of tumor-infiltrating lymphocytes (TILs) in HPV positive (HPV(+)) tumors. RNA-Sequencing (RNA-Seq) was used to evaluate whether the differences in clinical behaviour simply reflect a numerical difference in...
BACKGROUND Primary ovarian insufficiency (POI) is characterized by marked heterogeneity, but with a significant genetic contribution. Identifying exact causative genes has been challenging, with many discoveries not replicated. It is timely to take stock of the field, outlining the progress made, framing the controversies and anticipating future directions in elucidating the genetics of POI. ...
During meiosis, chromosomes acquire unique features: the two pairs of sister chromatids form axial elements (Aes) that synapse and form the synaptonemal complex (sC), telo-meres attach to the nuclear membrane where they form a cluster that later disassembles, meiotic recombination between the two pairs of sister chromatids happens and chiasmata are formed as an obligatory structure that keeps t...
Introduction Meiosis is a special type of cell division through which haploid gametes are generated from diploid parent cells. This is accomplished by a first division that induces homologous chromosome segregation followed by a second mitosis-like division that promotes sister chromatid separation. During the prophase of meiosis I, three basic events take place: pairing of homologous chromosom...
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