Comparing synaptic circuits and networks between brains of different animal groups helps us derive an understanding of how nervous systems might have evolved. The circuits of the startle response pathway in the brains of tailed vertebrates are known from electrophysiological studies on the giant reticulospinal Mauthner cells (M-cells). To identify morphological counterparts in chordate tunicate...

External factors such as radiation, drugs or chemotherapy can alter the expressions of a subset of genes. We call these genes the primarily affected genes. Primarily affected genes eventually can change the expressions of other genes as they activate/suppress them through interactions. Measuring the gene expressions before and after applying an external factor (i.e., perturbation) in microarray...

External factors such as radiation, drugs or chemotherapy can alter the expressions of a subset of genes. We call these genes the primarily affected genes. Primarily affected genes eventually can change the expressions of other genes as they activate/suppress them through interactions. Measuring the gene expressions before and after applying an external factor (i.e., perturbation) in microarray...

MOTIVATION Finding genes which are directly perturbed or targeted by drugs is of great interest and importance in drug discovery. Several network filtering methods have been created to predict the gene targets of drugs from gene expression data based on an ordinary differential equation model of the gene regulatory network (GRN). A critical step in these methods involves inferring the GRN from ...

The residual fraction the fraction of tracer extracted and retained by the myocardium after a bolus injection of "IN-labeled ammonia (NH, " NH+) was studied in isolated perfused rabbit hearts under conditions in which flow and cardiac metabolism could be selectively and independently controlled. Residual fraction and clearance (defined as the half-time [tl1⁄221 required for elimination of seque...

The residual fraction the fraction of tracer extracted and retained by the myocardium after a bolus injection of "IN-labeled ammonia (NH, " NH+) was studied in isolated perfused rabbit hearts under conditions in which flow and cardiac metabolism could be selectively and independently controlled. Residual fraction and clearance (defined as the half-time [tl1⁄221 required for elimination of seque...

1 EXECUTIVE SUMMARY In a low frequency analysis of vibration in a built-up structure, the eigen frequencies and the corresponding eigenmodes help the understanding of how and why the structure behaves as it does. These eigen solutions are also useful in calculations of forced response by modal super-position procedures. However, as frequency increases there are more and more modes with increasi...

Background: GCA is characterized by cranial symptoms but imaging techniques show that patients with non-specific such as systemic inflammation or PMR may have undiagnosed large vessel (LV) 1 . Although silent in clinically isolated consequences for patients’ outcome, little known about its prevalence and characteristics of affected patients. Objectives: To review data on the newly diagnosed wit...

I am writing this editorial on a very wintery day in Hobart, Tasmania, after returning from convivial and interesting week at the Institute of Australian Geographers’ annual conference, held unceded lands Whadjuk people Noongar Nation Bentley campus Curtin University Perth. Organised by team Western Australia led Tod Jones Kirsten Martinus, conference theme was coexistence, collaboration, geogr...