OBJECTIVES SSc-associated pulmonary hypertension (SSc-PH) has a worse prognosis compared with SSc without PH (SSc-nonPH). Iron deficiency (ID) was previously associated with worse clinical outcome and survival in other types of PH, but ID effects in SSc-PH are unknown. Therefore we investigated the prevalence and clinical significance of ID in systemic sclerosis patients with and without PH. ...

Pulmonary hypertension due to heart failure with preserved ejection fraction (PH-HFpEF) has been poorly studied in patients with systemic sclerosis (SSc). We sought to compare clinical characteristics and survival of SSc patients with PH-HFpEF (SSc-PH-HFpEF) versus pulmonary arterial hypertension (SSc-PAH). We hypothesized that patients with SSc-PH-HFpEF have a similar poor overall prognosis co...

Measurement shows that 85% of TCP flows in the internet are short-lived flows that stay most of their operation in the TCP startup phase. However, many previous studies indicate that the traditional TCP Slow Start algorithm does not perform well, especially in long fat networks. Two obvious problems are known to impact the Slow Start performance, which are the blind initial setting of the Slow ...

in this paper, startup performance of upflow anaerobic hybrid reactor and upflow anaerobic sludge blanket reactors in anaerobic treatment of distillery spentwash has been studied under identical conditions of operation. various effluent characteristics like ph, electrical conductivity, chemical oxygen demand, biochemical oxygen demand and total solids and other process parameters like biogas pr...

Containerized applications are becoming increasingly popular, but unfortunately, current containerdeployment methods are very slow. We develop a new container benchmark, HelloBench, to evaluate the startup times of 57 different containerized applications. We use HelloBench to analyze workloads in detail, studying the block I/O patterns exhibited during startup and compressibility of container i...

aim : we described two case reports of aih/ssc overlap syndrome and reviewed literatures regarding this issue.   background : aih is a chronic hepatitis of unknown aetiology characterized by continuing hepatocellular necrosis and inflammation. aih overlap syndromes have been reported with other autoimmune diseases. patients and methods : according to the classification criteria for ssc, we cond...

Small RNA duodenal libraries were constructed for Escherichia coli F18-sensitive and -resistant weaned piglets in full-sib pair groups and sequenced using Illumina Solexa high-throughput sequencing technology. The identification of differentially expressed miRNAs provides the basis for improved database information on pig miRNAs, understanding the genetic basics of differences in resistance to ...

Recognition of pulmonary arterial hypertension (PAH) associated with systemic sclerosis (SSc) (SSc-PAH) is very important , because SSc-PAH is highly prevalent and is a leading cause of mortality in patients with SSc. 1)2) Despite the use of novel therapeutic strategies, response to PAH-targeted therapy is still insufficient in SSc-PAH, which is associated with poor prognosis in SSc-PAH. 3) Ind...

OBJECTIVE To investigate the role of junctional adhesion molecule-A (JAM-A) in the pathogenesis of systemic sclerosis (SSc). METHODS Biopsy specimens from proximal and distal arm skin and serum were obtained from patients with SSc and normal volunteers. To determine the expression of JAM-A on SSc dermal fibroblasts and in SSc skin, cell surface ELISAs and immunohistology were performed. An EL...