Fractal image compression was one of the earliest compression schemes to take advantage of image redundancy in scale. The theory of iterated function systems motivates a broad class of fractal schemes but does not give much guidance for implementation. Fractal compression schemes do not t into the standard transform coder paradigm and have proven di cult to analyze. We introduce a wavelet-based...

We recently demonstrated that squalene synthase (SQS) inhibitors reduce plasma triglyceride through an LDL receptor-independent mechanism in Watanabe heritable hyperlipidemic rabbits (Hiyoshi et al. 2001. Eur. J. Pharmacol. 431: 345-352). The present study deals with the mechanism of the inhibition of triglyceride biosynthesis by the SQS inhibitors ER-27856 and RPR-107393 in rat primary culture...

BACKGROUND Self-quantification is seen as an emerging paradigm for health care self-management. Self-quantification systems (SQS) can be used for tracking, monitoring, and quantifying health aspects including mental, emotional, physical, and social aspects in order to gain self-knowledge. However, there has been a lack of a systematic approach for conceptualising and mapping the essential activ...

INTRODUCTION Multiple scoring systems have been proposed for prostate MRI reporting. We sought to review the clinical impact of the new Prostate Imaging Reporting and Data System v2 (PI-RADS) and compare those results to our proposed Simplified Qualitative System (SQS) score with respect to detection of prostate cancers and clinically significant prostate cancers. METHODS All patients who und...

BACKGROUND An evaluation of an effective and engaging intervention for educating general practice (GP) receptionists about integrated care and the importance of their role within the whole system was conducted. METHODS Workshops took place in North West London, one of England's 14 'Integrated Care Pioneers.' Three training days featuring Sequential Simulations (SqS) were held. Forty GP recept...

Irradiation damage to zirconium alloys (e.g., niobium (Zr-Nb) alloy) is the key design of fission-reactor structural materials and fuel rod cladding materials. Atomic scale computational simulations such as molecular dynamics first principles are often needed understand physical mechanism irradiation damage. For simulation randomly substitutional solid solution, it necessary construct large-siz...

Deterministic and probabilistic risk assessments were developed for commercial LAS in agricultural soil amended with sewage sludge. The procedure done according to ILSI Europe's Conceptual Framework [Schowanek, D., Carr, R., David, H., Douben, P., Hall, J., Kirchmann, H., Patria, L., Sequi, P., Smith, S., Webb, S.F., 2004. A risk-based methodology for deriving quality standards for organic cont...

UNLABELLED Hepatitis C virus (HCV) exploits host membrane cholesterol and its metabolism for progeny virus production. Here, we examined the impact of targeting cellular squalene synthase (SQS), the first committed enzyme for cholesterol biosynthesis, on HCV production. By using the HCV JFH-1 strain and human hepatoma Huh-7.5.1-derived cells, we found that the SQS inhibitors YM-53601 and zarago...