BACKGROUND IgA nephropathy (IgAN) can be complicated by nephrotic syndrome. Because the spontaneous resolution of heavy proteinuria is rare, corticosteroid therapy should be considered in such cases, particularly when IgAN is combined with minimal-change disease. Here, we report our experience of spontaneous remission of nephrotic syndrome in patients with IgAN and the long-term outcomes of the...

A 48-year-old male presented with an acute change in mental status due to a marked elevation of plasma NH3 and was diagnosed with citrullinemia with amino acid analysis of blood. Hemodialysis and hemodiafiltration were performed, but serum chemical analysis did not show any improvement which led us to terminate dialysis following intensive care for 3 days. Surprisingly, NH3 level had decreased ...

D efining a drug is an easy task: It is a molecule delivered to the body to produce a biological effect. Its mode of action is to alter one or more biochemical pathways, for instance, by binding to a receptor or by modifying the activity of an enzyme. Defining a placebo is a bit more complicated. A placebo is usually defined in pharmacological terms as an inert substance with no pharmacological...

Like other manifestations of the rheumatic state chorea is subject to spontaneous remissions and relapses which make the assessment of the action of any particular therapy notoriously difficult. Furthermore, objective measurements of the degree of chorea seem necessary to confirm clinical impressions of an increase or decrease of chorea. With this in mind certain objective methods of assessing ...

BACKGROUND The age-dependent change in atopic dermatitis (AD) at an individual level has mostly performed in a hospital-setting. OBJECTIVE We evaluated the age-dependent change of AD symptoms at an individual level in a community-setting. METHODS For the diagnostic accuracy, all participants of schoolchildren were received skin examination by dermatologists (twice a year for the same group)...

The most recent massage therapy (MT) study by Hernandez-Reif et al. displays flaws persistent in this area of research that are attributable to MT researchers' frequent mistake of using within-group analyses of dependent variables in studies that are purported to be randomized control trials. This practise violates the logic of using randomization to create treatment and control groups, and the...