BACKGROUND Inflammatory myofibroblastic tumor (IMT) is a neoplasm of unknown etiology occurring at various sites. By definition, it is composed of spindle cells (myofibroblasts) with variable inflammatory component, hence the name is IMT. CASE PRESENTATION The present case is of a 46 years old woman presented with a history of flank pain, abdominal mass and intermittent hematuria for last 6 m...

Dendritic fibromyxolipoma is a rare and distinctive soft tissue neoplasm that is considered by many authors as a variant of spindle cell lipoma and characterized by the presence of dendritic cytoplasmic processes, plexiform vascular pattern, and keloidal collagen. It has never been reported in the larynx and hypopharynx. Its rarity and the potential to mistake it as a more clinically aggressive...

A mucinous tubular and spindle cell carcinoma (MTSCC) is a rare and recently described kidney neoplasm with distal nephron differentiation. It can affect patients of all ages and is more prevalent among women. In this case report, we present a 50-year-old woman who had a renal mass, which was accidently discovered during an investigation for chronic anemia. The final diagnosis of MTSCC was made...

We report a unique case of a malignant peripheral nerve sheath tumor with glandular differentiation arising in the tibial epiphysis of a 30 year old woman with no other significant medical history. Extensive histochemical and immunohistochemical analysis showed the epithelium lining the glands to exhibit gastrointestinal and neuroendocrine differentiation. The patient’s clinical course had been...

PEComas localized in the region of falciform ligament and broad ligament are exceedingly rare. Most of them are built of spindle neoplastic cells. We report a case of epithelioid PEComa of the falciform ligament and/or broad ligament. There is only one report of such neoplasm in English-language literature. Histologically, the tumor was composed of nests of epithelioid clear cells stained posit...

Myofibroma is a rare benign spindle cell neoplasm in children that usually affects both soft tissue and bone in the head and neck region. Approximately one third of these cases are seen within jaw bones as solitary lesions. Solitary intra-osseous myofibroma of the jaw bone shares its clinical, radiographic and histological features with other spindle cell tumors. The rarity of this lesion can m...

but distinctive lesion with uncertain malignant potential and unknown etiology. IMT has been reported in various anatomic sites, but is rare in genitourinary tract. Pathologically, the lesion is composed of dominant spindle cell proliferation with variable amounts of an inflammatory component. These spindle cells are now known to be myofibroblasts, which account for the current designation for ...

The light microscopic and immunohistochemical characteristics of a case of fibrous histiocytoma of intermediate malignancy arising from the parotid gland are presented. This neoplasm is rare in this site and must be distinguished from other spindle cell tumors of the parotid gland, particularly those of epithelial and myoepithelial origins. Histologic characteristics similar to those displayed ...

Malignant fibrous histiocytoma (MFH), a type of sarcoma, is a malignant neoplasm of uncertain origin that arises both in soft tissue and bone. We present a case of MFH in a 18-year-oldfemale patient with swelling on the left maxillary posterior region .This paper demonstrates the malignant character of this neoplasm. CT scans revealed a clouding lesion in the left maxillary premolar and molar r...

Introduction: Submandibular region is surgically significant in the head and neck field and a mass in this region may have multiple differential diagnoses.   Case Report: An elderly man came with a single 4×2.5 cm swelling in the neck on the right side, just below the lower jaw, since one month. Ultrasound showed an irregular heterogeneous hypoechoic les...