Background: Effect of different doses of cysteamine on rate of in vitro maturation (IVM), in vitro fertilization (IVF) and glutathione (GSH) level was studied. Metaphase II (MII) spindle area was analyzed for quantification of shape and size of oocytes. Methods: Female mice were primed with 5 IU of pregnant mare’s stimulating gonadotrophin. Germinal vesicle (GV) oocytes were retrieved 48 hrs la...

background: effect of different doses of cysteamine on rate of in vitro maturation (ivm ) , in vitro fertilization (ivf ) and glutathione (gsh ) level was studied. metaphase ii (mii) spindle area was analyzed for quantification of shape and size of oocytes.   methods: female mice were primed with 5 iu of pregnant mare’s stimulating gonadotrophin . germinal vesicle (gv ) oocytes were retrieved 4...

Primary spindle cell sarcoma in the heart is a very uncommon disease. Although primary atrial or pulmonary vein spindle cell sarcomas have been sporadically reported, pericardial spindle cell sarcoma is rarely seen in currently available data. The commentary here is on a primary pericardial spindle cell sarcoma that was preliminarily misjudged to be left main coronary artery disease.

Primary thyroid spindle cell tumors or spindle cell component in the thyroid tumors are very rare. The spindle tumor cells were positive for thyroid papillary carcinoma markers. So these tumors were diagnosed as spindle cell variant of papillary thyroid carcinoma (PTC). To further delineate clinico-pathological features of primary thyroid spindle cell tumors and discuss differential diagnosis, ...

INTRODUCTION During cell division, the mitotic spindle captures chromosomes and segregates them into two equal sets. The orientation and position of the mitotic spindle is important because the spindle equator becomes the plane of cell division. For instance, in a columnar cell with apical and basal polarity, if the spindle pole-to-pole axis orients along the cell’s long axis, the cell will div...

Dividing epithelial cells need to coordinate spindle positioning with shape changes to maintain cell-cell adhesion. Microtubule interactions with the cell cortex regulate mitotic spindle positioning within the plane of division. How the spindle crosstalks with the actin cytoskeleton to ensure faithful mitosis and spindle positioning is unclear. Here we demonstrate that the tumour suppressor DLC...

Spindle-cell differentiation in ameloblastic carcinoma is a rare event. Although reported by many authors, it was first described as a separate entity in 1999 by Slater under the heading "low-grade spindle-cell ameloblastic carcinoma." Here, we report a case of low-grade spindle-cell ameloblastic carcinoma arising in pre-existing unicystic ameloblastoma.The patient, a 60-year-old Indian woman, ...

it was first introduced by Enzinger and Harvey (1). The three principal components of spindle cell lipoma are mature adipocytes, small, undifferentiated spindle cells and short bundles of brightly eosinophilic collagen that are associated with the spindle cells. The relative proportion of these three elements within a given lesion varies quite markedly, with the spindle cell areas accounting fo...