Background: Metastasis of systemic neoplasms to the spine is common; however, metastasis primary spinal cord tumors other regions in body an infrequent occurrence. A few case reports have described tumors, and most cases, patients were younger than 30 years age. Case Description: We present illustrative a 47-year-old female with metastatic lesions lumbosacral vertebrae after initial diagnosis i...

Ethmoid adenocarcinoma is the most frequent ethmoid tumor. To date, only a single case of spinal cord compression resulting from ethmoid adenocarcinoma has been reported. The current case study presents a recent case of vertebroepidural metastasis of an ethmoid adenocarcinoma leading to spinal cord compression. Modern imaging studies, including magnetic resonance imaging (MRI) and 18 fludeoxygl...

OBJECTIVE Cancer of the spinal cord is highly malignant and often leads to paralysis and death. A realistic mouse model would be an important benefit for the better understanding and treatment of spinal cord glioma. MATERIALS AND METHODS To develop an imageable, patient-like model of this disease, U87 human glioma tumour fragments (expressing red fluorescent protein), were transplanted by sur...

With the progress of image-guided localization, body immobilization system, and computerized delivery of intensity-modulated radiation delivery, it became possible to perform spine radiosurgery. The next question is how to translate the high technology treatment to the clinical application. Clinical trials have been performed to demonstrate the feasibility of spine radiosurgery and efficacy of ...

Ovarian cancer metastasis to the spinal cord is quite rare, and few case reports have been published previously. Herein, we present a case of a patient who was treated for ovarian cancer and was thought to be disease free for 17 months, then presented with lower limb weakness. She was found to have a T11-T12 metastatic intramedullary spinal cord lesion. On pathology, the diagnosis of metastatic...

v Svensk sammanfattning vi Abbreviations viii List of papers ix Thesis at a glance x Introduction 1 Prostate cancer epidemiology 1 Bone metastasis in prostate cancer 3 Metastatic mechanisms 3 Interactions between prostate cancer cells and bone 4 Metastatic spinal cord compression 6 Frequency 6 Localization 6 Pathophysiology 6 Clinical symptoms 8 Diagnosis 9 Prognosis 9 Treatment 10 Spinal cord ...

SCC occurs as a result of a malignant neoplasm compressing the spinal cord. Malignant tumors may be classified as primary (i.e., arising from the tissue of the spinal cord or spinal canal) or secondary (i.e., arising as metastatic solid tumors) (Schafer, 1997). SCC most commonly is caused by metastatic tumors. Progression of symptoms is more rapid with metastatic tumors when compared to primary...

cortical spreading depression (csd) has been suggested to underlie some neurological disorders such as migraine. despite the intensity with which many investigators have studied sd in the brain, only a few studies have aimed to identify sd in the spinal cord. here we described the main characteristic features of sd in the spinal cord induced by different methods including various spinal cord in...