Even in cases of spinal cord injury (SCI) where sensory perceptions do not arise from stimuli applied to below-level regions, sensory input to the spinal cord, carried by spinal sensory afferents, still occurs and influences the central and autonomic nervous systems (CNS, ANS). This is true also of the vagal system which provides non-spinal innervation of viscera below many spinal cord injuries...

Background: As a novel pro-apoptotic kinase, Mammalian sterile 20–like kinase 1 (Mst1) promotes programmed cell death in animal models of inflammatory diseases. This research aimed to determine the level of expression of Mst1 gene in a rat model of spinal cord injury (SCI) treated with valproic acid (VPA). Methods: Animals were divided into four groups: Contused animals (untreated); laminectom...

Spinal cord injury (SCI), in addition to motor and sensory problems, may also lead autonomic dysfunction. Postural orthostatic tachycardia syndrome (POTS) is one of them has often been reported traumatic brain injuries, multiple sclerosis, other spinal pathologies. However, there not much data on POTS SCI even extensive databases. We present a case an adolescent female with paraplegia due SCI. ...

introduction: spinal cord injuries (sci) lead to permanent irreversible functional deficits.  poor prognosis of patients is the motivation of searching a treatment for the chronic injury.  planting stem cells provides us with a promising strategy. in the meanwhile, the use of olfactory ensheathing cells (oecs) has shown very good results.  this study aims at evaluating the effect of transplante...

background: bone marrow stromal cells (bmsc) have been successfully employed for movement deficit recovery in spinal cord injury (sci) rat models. one of the unsettled problems in cell transplantation is the relative high proportion of cell death, specifically after neural differentiation. according to our previous studies, p75 receptor, known as the death receptor, is only expressed in bmsc in...

spinal cord injury (sci) leads to a significant health problem associated with a broad range of secondary complications and disabilities. in this regard, animal models can help us to understand the pathobiology of sci and evaluate the effects of potential treatments for sci. in contusion models of sci, different devices including surgical spring-loaded clips, balloons, forceps, weights and the ...

One third of all spinal injuries involve cervical vertebrae, and the impact of injury to the cervical spinal cord is profound and requires systemic treatment. The role and timing of surgical decompression after an acute spinal cord injury (SCI) remains one of the most controversial topics pertaining to spinal surgery. Lack of controlled, prospective, multicenter clinical studies has contributed...

BACKGROUND In recent decades, the incidence of spinal cord injuries has increased. In a systemic review on epidemiology of traumatic spinal cord injury in developing countries reported 25.5/million cases per year. OBJECTIVES To assess the quality of life (QOL) of the veterans among Iran-Iraq war with chronic spinal cord injuries (SCI) and to evaluate long-term impressions of SCI on their qual...

Spinal Cord Injury .........................................1-3 Implementation Of The Year 2000 AgeAdjustment Standard ....................................4-6 Spinal Cord Injury (SCI) is one of the most debilitating types of trauma. Disability, loss of productivity, extreme use of medical resources, and untold human suffering routinely accompany these injuries. In order to assess the need for s...

Use of genetically modified mice enhances our understanding of molecular mechanisms underlying several neurological disorders such as a spinal cord injury (SCI). Freehand manual control used to produce a laceration model of SCI creates inconsistent injuries often associated with a crush or contusion component and, therefore, a novel technique was developed. Our model of cervical laceration SCI ...