BACKGROUND Dementia with Lewy bodies (DLB) is one of the main differential diagnoses of Alzheimer's disease (AD). Key pathological features of patients with DLB are not only the presence of cerebral cortical neuronal loss, with Lewy bodies in surviving neurones, but also loss of nigrostriatal dopaminergic neurones, similar to that of Parkinson's disease (PD). In DLB there is 40-70% loss of stri...

Early diagnosis of osteomyelitis and prosthetic bone infection is essential for successful therapy and prevention of complications. Nuclear medicine offers a variety of modalities for this aim, including both single photon emission tomography (SPET) and positron emission tomography (PET) radiopharmaceuticals. The main limitation of these functional images is the fact that they are lacking the s...

Nuclear medicine techniques designed to identify bone metastases are reviewed. They include planar and whole body, single photon emission tomography (SPET), F-18 Fluorine and FDG, deoxyglucose, positron emission tomography (PET), bone imaging.

Fusion genes are known to be key drivers of tumor growth in several types of cancer. Traditionally, detecting fusion genes has been a difficult task based on fluorescent in situ hybridization to detect chromosomal abnormalities. More recently, RNA sequencing has enabled an increased pace of fusion gene identification. However, RNA-Seq is inefficient for the identification of fusion genes due to...

This is the first case of Graves' disease in an adolescent with lingual and prelaryngeal dual congenital ectopia and no orthotopic thyroid gland identified by technetium-99m-pertechnetate (99mTcO-4) SPET/CT imaging in a 15 years old boy. After 8 weeks treatment with methimazole, Graves' disease subsided. Fine needle aspiration cytology of the mass revealed the normal colloid and normal follicul...

Monte Carlo methods are extensively used in Nuclear Medicine to tackle a variety of problems that are difficult to study by an experimental or analytical approach. A review of the most recent tools allowing application of Monte Carlo methods in single photon emission tomography (SPET) and positron emission tomography (PET) is presented. To help potential Monte Carlo users choose a code, we pres...

BACKGROUND The second survey of nuclear cardiology in the Czech Republic was conducted to ascertain whether the activity had increased since the first survey in 2001; we also intended to identify new trends in clinical practice. MATERIALS AND METHODS All 46 departments of nuclear medicine in the Czech Republic completed a questionnaire concerning nuclear cardiology activity in 2002-2003 and c...

We present a 42-year-old patient who was examined in the Gastroenterology Department of Gaziantep University for chronic abdominal pain, nausea and vomiting. Ultrasonography showed a 4.7 cm solid hepatic mass on the right lateral side of the right lobe of the liver. The patient was then sent to the Nuclear Medicine Department of Gaziantep University for liver scan. After injecting autologous re...