background physical activity and alteration of temperature as a source of stress may have adverse effects on male reproduction. objectives the aim of this study was to investigate the effect of chronic swimming and standing in cold, warm and lukewarm water on mouse spermatogenesis. materials and methods forty-nine male mice (n = 49) were randomly divided into seven groups: c, control; swc, swim...

The Sertoli cell, which is the supporting cell of spermatogenesis, has an important role in the endocrine and paracrine control of spermatogenesis. Functionally, it provides the cells of the seminiferous epithelium with nutrition, conveys mature spermatids to the lumen of seminiferous tubules, secretes androgen‑binding protein and interacts with endocrine Leydig cells. In addition, the levels o...

In this study we investigate the expression pattern of mucin genes in the human testis and evaluate the relationship between the expression of mucin genes and impaired spermatogenesis in the human testis. Thirty human testis tissues were collected from patients undergoing diagnostic testicular biopsy to investigate the cause of infertility. One part of the tissue underwent histological observat...

4 Androgens.hormonal regulation of spermatogenesis, with an emphasis on the role of testosterone within the. Hormonal messengers are critical not only for regulation of.Spermatogenesis. Cell types involved in sperm production. How they interact to support spermatogenesis. Hormonal regulation of spermatogenesis.ISBN 951-29-2337-8 Print, ł Īī-Ī PDF. The expression and hormonal regulation of beta-...

Many experimental animal models are available for analyzing the process of spermatogenesis, including transgenic animals and strains that inherently lack spermatogenesis [2,3]. In contrast, several experimental systems for inducing spermatogenesis in vitro or in vivo have only been developed in recent decades [4-10] for use as tools for studying the fundamental aspects of spermatogenesis and as...

Spermatogenesis is regulated by the 2 pituitary gonadotropins, luteinizing hormone (LH) and follicle-stimulating hormone (FSH). This process is considered impossible without the absolute requirement of LH-stimulated testicular testosterone (T) production. The role of FSH remains unclear because men and mice with inactivating FSH receptor (FSHR) mutations are fertile. We revisited the role of FS...

Effect of ginger (Zingiber officinale R.) on metiram-inhibited spermatogenesis and induced apoptosis in albino miceSaber A. Sakr, Gamal M. Badawy

1960’s I. Control of Human Spermatogenesis Intrascrotal Temperature The authors showed that alterations of intrascrotal temperature markedly affect spermatogenesis and sperm counts. In euspermic subjects, scrotal exposure for 30 minutes to a 150-watt electric light bulb resulted in reversal of the scrotal-rectal temperature ratio by a mean of 2.9 °C. Such treatment on 14 consecutive days caused...

Thyroid hormones, previously thought not to affect spermatogenesis and male fertility, are now being recognized as having important role in spermatogenesis. The identification of thyroid hormone receptors on Sertoli cells, the nurturing cells for sperm in the testis, has embarked further research to investigate the role of thyroid hormones in male reproduction. Since spermatogenesis occurs in c...

Spermatogenesis is a long andcomplexprocess that, despite the sharedoverall goal of producing themale gamete, displays striking amounts of interspecific diversity. In this review, we argue that sperm competition has been an important selection pressure acting on multiple aspects of spermatogenesis, causing variation in the number andmorphology of sperm produced, and in themolecular and cellular...