capacity was saturated by an acute intravenous infusion of iron, deposited a large fraction of intestinally absorbed iron in the liver during the first pass of portal venous blood through this organ.1 Subsequently, Wheby and Umpiere demonstrated similar results in normal human subjects given sufficient iron to acutely saturate their plasma iron-binding capacity.2 Our results in patients with sp...

A correlation has been established between the absorbed fraction of training-set molecules after oral administration in humans and the Quantum Mechanical Polar Surface Area (QMPSA). This correlation holds for the QMPSA calculated with structures where carboxyl groups are deprotonated. The correlation of the absorbed fraction and the QMPSA calculated on the neutral gas phase optimized structures...

A tensile split Hopkinson bar apparatus is developed for testing high strain rate behavior of glass-filled epoxy. The apparatus uses a specimen gripping configuration which does not require fastening and/or gluing and can be readily used for castable materials. Details of the experimental setup, design of grips and specimen, specimen preparation method, benchmark experiments, and tensile respon...

The sensitivity to different relevant parameters of the absorbed fraction of alpha particles emitted from the 222Rn chain in sensitive cells of the tracheo-bronchial tree have been investigated. The structure of the airway wall given by ICRP (ICRP66) has been adopted and employed in the present calculations. The source thickness (mucous gel and sol + cilia), target layer thickness and the depth...

Human peripheral blood leukocytes were stimulated with killed staphylococci in vitro to release leukocytic pyrogen (LP). Supernates from these stimulated leukocytes were concentrated, emulsified in Freund's complete adjuvant, and injected intradermally into rabbits. After seven monthly booster injections, rabbit antiserum destroyed the pyrogenic activity of human LP, and the titer of this neutr...

Considering heart as a unique organ that regulates blood flow, Ayurveda places specific emphasis on protecting the from numerous conditions might lead to development of various illnesses. It emphasizes need avoiding stress and promoting diet helps in boosting health. The role failure with low ejection fraction is discussed this paper. Low fraction, often known EF, occurs when your goes below 55...

Novel lead oxide-based flexible dosimeters with superior performance were experimentally tested for electron therapy. However, absorbed/transmitted primary particle fraction and secondary radiation distribution from the dosimeter surface have not been reported. These features should be specified to improve dosimeter’s reliability medical applications. Hence, absorbed fraction, transmitted radia...

UNLABELLED Dose assessment to active bone marrow is a critical feature of radionuclide therapy treatment planning. Skeletal dosimetry models currently used to assign radionuclide S values for clinical marrow dose assessment are based on bone and marrow cavity chord-length distributions. Accordingly, these models cannot explicitly consider energy loss to inactive marrow (adipose tissue) during p...

UNLABELLED Absorbed-dose calculations provide a scientific basis for evaluating the biologic effects associated with administered radiopharmaceuticals. In cancer therapy, radiation dosimetry supports treatment planning, dose-response analyses, predictions of therapy effectiveness, and completeness of patient medical records. In this study, we evaluated the organ radiation absorbed doses from in...

Rats at various ages were observed to present with different radiosensitivity and bioavailability for radiotracers commonly used in preclinical research. We evaluated the effect of age-induced changes in body weight on radiation dose calculations. A series of rat models at different age periods were constructed based on the realistic four-dimensional digital rat whole-body (ROBY) computational ...