INTRODUCTION Rheumatoid arthritis (RA) is associated with hypogalactosylation of immunoglobulin G (IgG). We examined whether a proxy measure for galactosylation of IgG N-glycans could predict response to therapy or was differentially affected by methotrexate (MTX) or TNF blockade. METHODS Using a previously defined normal phase high-performance liquid chromatography approach, we ascertained t...

OBJECTIVE To assess the reliability and validity of the Dutch version of the exercise self-efficacy scale (ESES) in persons with spinal cord injury. This is the first independent study of ESES psychometric properties, and the first report on ESES test-retest reliability. SUBJECTS/PATIENTS A total of 53 Dutch persons with spinal cord injury. METHODS Subjects completed the Dutch ESES twice, w...

Given a set V of n objects, an online ranking system outputs at each time step a full ranking of the set, observes a feedback of some form and suffers a loss. We study the setting in which the (adversarial) feedback is an element in V , and the loss is the position (0th, 1st, 2nd...) of the item in the outputted ranking. More generally, we study a setting in which the feedback is a subset U of ...

With computer simulations, we examined the performance of the Spearman-Kärber method for analyzing psychometric functions and compared this method with the standard technique of probit analysis. The Spearman-Kärber method was found to be superior in most cases. It generally yielded less biased and less variable estimates of the location and dispersion of a psychometric function, and it provided...

The objective of the present study was to utilise an accurate canine pedometer methodology and to assess the relationship between activity and body condition score (BCS) in dogs. Initial methodology validation used videography and pedometer step measurements to assess actual steps taken in comparison with pedometer readings for twenty large, medium and small dogs. During the validation, dogs co...

A pair of linear orders L, L′ on an n-element set V is a concordance pair if the Kendall and Spearman correlation measures between L and L′ coincide. A graph is called concordance graph if it has the same number of induced three-vertex one-edged subgraphs as induced three-vertex twoedged subgraphs. It is known (see Fishburn and Monjardet (2000)) that (L, L′) is a concordance pair if and only if...

One of the most commonly used statistical methods is bivariate correlation analysis. However, it usually case that little or no attention given to power and sample size considerations when planning a study in which will be primary In fact, we reviewed studies published clinical research journals 2014, found none 111 articles presented results analyses included justification. It sometimes intere...

Based on the trivariate reduction technique two different trivariate Bernoulli mixtures of univariate uniform distributions and their associated trivariate copulas with bivariate linear Spearman marginal copulas are considered. Mathematical characterizations of these Bernoulli mixture models are obtained. Since Bernoulli mixture trivariate reduction copulas are not compatible with all valid gra...

We propose a CUSUM type test for constant correlation that goes beyond a previously suggested correlation constancy test by considering Spearman’s rho in arbitrary dimensions. By using copula-based expressions, we simultaneously extend a previously suggested copula constancy test. We calculate the asymptotic null distribution using an invariance principle for the sequential empirical copula pro...