BACKGROUND Breast cancer has been the subject of many recent studies because it is a significant cause of death in women. This study was performed to clarify whether solitary skeletal metastasis has clinical significance compared with multiple skeletal metastasis. PATIENTS AND METHODS Seven hundred and three patients who developed metastatic bone lesions up to September 2002 after beginning t...

Locusts demonstrate remarkable phenotypic plasticity driven by changes in population density. This density dependent phase polyphenism is associated with many physiological, behavioral, and morphological changes, including observations that cryptic solitarious (solitary-reared) individuals start to fly at dusk, whereas gregarious (crowd-reared) individuals are day-active. We have recorded for 2...

Bronchopulmonary C fibers defend the lungs against injury from inhaled agents by a central nervous system reflex consisting of apnea, cough, bronchoconstriction, hypotension, and bradycardia. Glutamate is the putative neurotransmitter at the first central synapses in the nucleus of the solitary tract (NTS), but substance P, also released in the NTS, may modulate the transmission. To test the hy...

The ubiquitous trade-off between survival and costly reproduction is one of the most fundamental constraints governing life-history evolution. In numerous animals, gonadotropic hormones antagonistically suppressing immunocompetence cause this trade-off. The queens of many social insects defy the reproduction-survival trade-off, achieving both an extraordinarily long life and high reproductive o...

In a two-uid system where the lower uid is bounded below by a rigid bottom and the upper uid is bounded above by a free surface, two kinds of solitary waves can propagate along the interface and the free surface: classical solitary waves characterized by a solitary pulse or generalized solitary waves with nondecaying oscillations in their tails in addition to the solitary pulse. The classical s...

The ambipolar radial electric field in a nonaxisymmetric plasma can be described by a nonlinear diffusion equation. This equation is shown to possess solitary wave solutions. A model nonlinear diffusion equation with a cubic nonlinearity is studied. An explicit analytic step-like form for the solitary wave is found. It is shown that the solitary wave solutions are linearly stable against all bu...