The activity of glyoxalase I from the soluble fraction of diabetic rat liver was found to decrease as compared to the control. Sodium orthovanadate in drinking water and Trigonella foenum graecum seed powder when administered to these diabetic animals were found to reverse the activity of glyoxalase I to control values. A combination of the above two antidiabetic compounds showed a better rever...

Vanadium is considered as an essential trace element in some animals. In human’s classification of vanadium as an essential nutrient is still a topic of debate among various research groups. Nutritionally vanadium is thought to be a cofactor in various enzymatic reactions. Increased levels of insulin in blood (hyperinsulinemia) associated with type-2 diabetes mellitus. Increase intake of fat in...

In many tissues, the level of cytoplasmic calcium mediates cell function. Since cytoplasmic calcium is often maintained at a low level by active calcium extrusion, we examined whether calcium-stimulated ATPase is present in the rabbit ciliary epithelium. A technique was developed to measure calcium-stimulated ATPase in a partially enriched plasma membrane preparation. The enhancement of Na,K-AT...

Biochemical and immunological analysis of unfertilized sea urchin eggs has revealed the presence of at least two distinct isoforms of cytoplasmic dyneins, one soluble and the other microtubule-associated. The soluble enzyme is a 20 S particle with a MgATPase activity that can be activated 5-fold by nonionic detergents. It contains heavy chain polypeptides that 1) comigrate with the dynein heavy...

Vanadium oxides are highly valued as electrochromic materials because of their multicolor capabilities. However, practical applications have been limited due to challenges such the dissolution vanadate into aqueous electrolytes, leading poor long-term stability. Herein, a solution is proposed issue by utilizing hybrid electrolyte consisting tetraethylene glycol dimethyl ether (TEGDME) and water...

Previous in vitro and in vivo studies have shown that sodium orthovanadate (vanadate), an inorganic vanadium compound, could effectively suppress radiation-induced p53-mediated apoptosis via both transcription-dependent and transcription-independent pathways. As a potent radiation protector administered at a dose of 20 mg/kg body weight (20 mg/kg) prior to total body irradiation (TBI) by intra-...

A new highly efficient, visible light active, silver vanadate/polymeric carbonitride “core/shell” photocatalyst was prepared mechano-chemically by grinding mixtures of β-silver vanadate and mesoporous graphitic carbonitride. Besides the core/shell photocatalyst, vanadate/mesoporous polymeric composites supported mpg-C3N4@β-silver vanadates were prepared. The materials characterized transmission...

Vanadate, a potent naturally occurring Na+,K+-ATPase inhibitor thought to have a role in regulating Na+-K+ pump activity, was fed to uninephrectomized rats drinking tap water or a 1% solution of sodium chloride for as long as 56 weeks. Feeding was achieved by adding sodium orthovanadate to normal rat chow equivalent to 100 or 200 ppm vanadium by weight. In the rats drinking tap water, systolic ...