This study aims to explore the potential pathways and molecular characteristics of fluorine-induced osteoblast apoptosis. In vitro fluorine-induced model was established with an osteogenesis sarcoma cell line Saos-2. Then flow cytometry was used to determine the mitochondrial membrane potential at 24 h after the intervention. 84 apoptosis-related genes in the cells were determined using the fun...

background: early childhood caries (ecc) in the earliest stage is preventable. the studies indicate oral bacteria play an important role in pathogenesis of dental caries. according to high prevalence of ecc, alternative therapies should be explored in order to reduce the occurrence of it. aim: this study aims to assess the effectiveness of a product containing povidone iodine 10% and sodium flu...

introduction: to compare the effects of 0.05% sodium fluoride (naf) mouthrinse, gc tooth mousse and gc mi paste plus on white spot formation inhibition. materials and methods: thirty pairs of extracted human premolars were cut in half mesio-distally with a disc. the teeth were coated with nail varnish, except a part of the buccal and/or lingual enamel, which was used as the test area, and then ...

1 2 Background: Application of topical fluoride agents has been shown to be the most effective method in 3 treating demineralized enamel after in-office bleaching treatments. Thus, this study aimed to examine the 4 effects of two different post-bleaching fluoridation agents (1.5% titanium tetrafluoride and 2.1% sodium 5 fluoride) on the calcium loss of enamel after an acidic challenge. 6 Method...

Background: Malva sylvestris L. (M. sylvestris) has antioxidant property and is widely used in the traditional medicine to treat gastrointestinal, respiratory, skin and urological disorders. Objective: In this study, the protective effect of M. sylvestris against sodium fluoride-induced nephrotoxicity in the rat was evaluated. Methods: The M. sylvestris flower extract was prepared and in...

The study was carried out to evaluate the neuropathological effect of sodium fluoride in hippocampus of albino rat. Healthy albino rats of Wistar strain weighing 100-200 g were divided in four groups. Group I was given 1 ml double distilled deionized water/kg body weight/day for forty days and kept as control. The remaining groups II, III and IV were treated with 100, 200 and 300 ppm of sodium ...

the aim of the present study was to evaluate vitamin c (vc) as a potent natural antioxidant to mitigate the genotoxic effects of arsenic trioxide and sodium fluoride in swiss albino mice in vivo. the study was divided into eight groups consisting of control treated with normal saline (group i), group ii, iii, iv, v, vi, vii and the vc group with only vitamin c (500 mg/kgbw). arsenic trioxide (4...

OBJECTIVE To detect the anticandidal activity of nine toothpastes containing sodium fluoride, sodium monofluorophosphate and herbal extracts as an active ingredients against 45 oral and non oral Candida albicans (C. albicans) isolates. METHODS The antifungal activity of these toothpaste formulations was determined using a standard agar well diffusion method. Statistical analysis was performed...

background and aims. a carious lesion is the accumulation of numerous episodes of de- and remineralization, rather than a unidirectional demineralization process. tooth destruction can be arrested or reversed by the frequent delivery of fluoride or calcium/phosphorous ions to the tooth surface. the present study compared and evaluated the remineralization potential of sodium fluoride and bioact...