We perform model independent and model dependent analyses of solar neutrino data including the neutral current event rate from SNO. The inclusion of the first SNO NC data in the model independent analysis determines the allowed ranges of B flux normalisation and the νe survival probability more precisely than what was possible from the SK and SNO CC combination. We perform global νe − νactive o...

A nanoscale coating of a Si layer on the pore walls of SnO(2) nanotubes (Si-coated SnO(2)) leads to very good electrochemical performance in coulombic efficiency, rate capability and capacity retention compared with untreated SnO(2) nanotubes.

S-nitrosoalbumin (SNO-Alb) is a major reservoir of releasable nitric oxide (NO) in plasma. In preeclampsia, a pregnancy-specific disorder associated with endothelial dysfunction, we previously found significant elevations in plasma SNO-Alb concentrations and decreased plasma ascorbate (Asc) levels. This increased SNO-Alb may result from low-plasma Asc if Asc, along with transition metals (eg, c...

Previous studies have shown a role for nitric oxide and S-nitrosylation (SNO) in postconditioning (PostC), but specific SNO proteins and sites have not been identified in the myocardium after PostC. In this study, we examined SNO signaling in PostC using a Langendorff-perfused mouse heart model. After 20 min of equilibrium perfusion and 25 min of global ischemia, PostC was applied at the beginn...

The proto-oncogene Sno has been shown to be a negative regulator of transforming growth factor beta (TGF-beta) signaling in vitro, using overexpression and artificial reporter systems. To examine Sno function in vivo, we made two targeted deletions at the Sno locus: a 5' deletion, with reduced Sno protein (hypomorph), and an exon 1 deletion removing half the protein coding sequence, in which Sn...

Banked blood exhibits impairments in nitric oxide (NO)-based oxygen delivery capability, reflected in rapid depletion of S-nitrosohemoglobin (SNO-Hb). We hypothesized that transfusion of even freshly-stored blood used in pediatric heart surgery would reduce SNO-Hb levels and worsen outcome. In a retrospective review (n = 29), the percent of estimated blood volume (% eBV) replaced by transfusion...

p53 is a master tumour repressor that participates in vast regulatory networks, including feedback loops involving microRNAs (miRNAs) that regulate p53 and that themselves are direct p53 transcriptional targets. We show here that a group of polycistronic miRNA-like non-coding RNAs derived from small nucleolar RNAs (sno-miRNAs) are transcriptionally repressed by p53 through their host gene, SNHG...

The paper reports the preparation and photocatalytic activity of ZnO doped SnO2 nanoparticles. These nanoparticles were synthesized by hydrothermal method. The products were characterized by X-ray diffraction (XRD) and scanning electron microscopy (SEM). Their grain sizes are about 50-100 nm. The characterization results revealed that the synthesized nanoparticles possess just cr...

SnO nanoparticles were synthesized using microwave–assisted hydrothermal method. It was noticed that at 300 and 600 watt microwave power, SnO formed and remained in the tetragonal phase. At 900 watt, SnO2 started appearing and a mixture of SnO and SnO2 phases coexisted. The particle size varied from ~2 to ~13 nm at 300 to 900 watt radiation power. The UV-V absorption spectra showed the excitoni...

Nitric oxide (NO) plays an important role in cardioprotection, and recent work from our group and others has implicated protein S-nitrosylation (SNO) as a critical component of NO-mediated protection in different models, including ischemic pre- and post-conditioning and sex-dependent cardioprotection. However, studies have yet to examine whether protein SNO levels are similarly increased with p...