Abstract Microfluidic devices offer unique opportunities to directly observe multiphase flow in porous media. However, as a representation of geological pore networks, conventional microfluidics face several challenges. One is whether steady simultaneous two-phase through two-dimensional network possible without fluctuating occupancy the constrictions. Flow fluctuations can occur only if paths ...

According to the requirements of carbon-neutral development, this study explores comparison and new discussion replacing nitrogen with carbon dioxide in conventional two-phase microfluid flow. Thus, application various fields can be more precise convenient. This research uses an artificially continuously tapering micro model mimic natural rock channel low permeability formation, where liquid im...

abstract background: clinical risk index of babies (crib), score for neonatal acute physiology (snap), an update of the clinical risk index for babies score (crib ii) and score for neonatal acute physiology - perinatal extension (snap-pe) are scoring devices developed in neonatal intensive care units. this study reviewed these scoring systems in critically ill neonates to determine how well the...

This study was designed to compare the ultraportable mechanically powered Smart Negative Pressure (SNaP) Wound Care System (Spiracur, Sunnyvale, CA) with the electrically powered Vacuum-Assisted Closure (VAC) Therapy System (Kinetic Concepts, Inc. [KCI], San Antonio, TX) in a multicenter, comparative efficacy, noninferiority-powered, randomized controlled trial. We enrolled 132 people with noni...

Although there is significant evidence supporting the use of negative pressure wound therapy (NPWT) for the treatment of lower extremity diabetic ulcers, currently available electrically powered NPWT systems are not ideally suited for treating smaller diabetic foot ulcers. The Smart Negative Pressure (SNaP) Wound Care System is a novel, ultraportable device that delivers NPWT without the use of...

In vitro display technologies have proved to be powerful tools for obtaining high-affinity protein binders. We recently described SNAP display, an entirely in vitro DNA display system that uses the SNAP-tag to link protein with its encoding DNA in water-in-oil emulsions. Here, we apply SNAP display for the affinity maturation of a designed ankyrin repeat proteins (DARPin) that binds to the extr...

the objective of this study was to determine the effects of grasp conditions (types of grasp, grasp width, glove and types of coupling) on maximal pushing force (mpf) and required pinch force (rpf) during snap fit assembly. the results indicated that the type of grasp, the type of coupling and wearing gloves have significant (p

A deep understanding of the pore-scale fluid flow mechanism during CO2 flooding process is essential to enhanced oil recovery (EOR) and subsurface sequestration. Two-phase simulations were performed simulate based on phase-field method in this study. Two-dimensional models with random positions sizes grains circular shape constructed reproduce topology porous media heterogeneous pore size distr...

The SNAP receptor (SNARE) complex, consisting of synaptosome-associated protein of 25 kDa (SNAP-25), synaptobrevin-2, and syntaxin-1, is involved in synaptic vesicles exocytosis. In addition, SNAP-25 has been implicated in constitutive exocytosis processes required for neurite outgrowth. However, at least three isoforms of SNAP-25 have been reported from neurons: SNAP-23, which is also present ...