Above ureteric orifices 3 layers – adventitia, smooth muscle, and urothelium. Haphazard arrangement of smooth muscle myofibrils. Acts as functional syncytium. No specific gap junctions, but ‘areas of close proximity’ 2 main populations of receptors, cholinergic (muscarinic) and adrenergic Muscarinic subtypes M2 and M3 in bladder smooth muscle. M2 80% population, but M3 functionally important Ad...