BACKGROUND Preclinical radiation biology has become increasingly sophisticated due to the implementation of advanced small animal image guided radiation platforms into laboratory investigation. These small animal radiotherapy devices enable state-of-the-art image guided therapy (IGRT) research to be performed by combining high-resolution cone beam computed tomography (CBCT) imaging with an isoc...

Background: The lack of lateral electronic disequilibrium (LED) becomes a main problem in small field. This factor affects the dose in target volume cannot predict correctly. In addition, utilization of high-energy linear accelerator (10 MV) can emit some unwanted particles (electron contamination). Therefore, the aim of this study was to characterize head linear accelerator (linac) Varian Clin...

To develop and apply a remote dosimetry protocol with PRESAGE® radiochromic plastic and optical-CT readout in the validation of MRI guided radiation therapy (MRgRT) treatments (MRIdian® by ViewRay®). Through multi-institutional collaboration we performed PRESAGE® dosimetry studies in 4ml cuvettes to investigate dose-response linearity, MRcompatibility, and energy-independence. An open calibrati...

Introduction: Penumbra is an important property of the radiation beam to obtain a suitable margin surrounding the target volume. Therefore, the precise penumbra width determination in stereotactic radiotherapy is necessary for treatment planning. This study aimed to compare the obtained results of penumbra width by in-house and standard circul...

Introduction: Inclusion of inhomogeneities such as air-filled cavities in the head and neck treatment fields may result in potential dosimetric disagreement which was caused by electronic disequilibrium. Most of treatments planning systems (TPS) are not able to predict dose distribution of inhomogeneous regions accurately. EBT2 films are used frequently in radiotherapy quality ass...

TG-69 is a task group report of the AAPM on the use of radiographic film for dosimetry. Radiographic films have been used for radiation dosimetry since the discovery of x-rays and have become an integral part of dose verification for both routine quality assurance and for complex treatments such as soft wedges (dynamic and virtual), intensity modulated radiation therapy (IMRT), image guided rad...

Light dosimetry is an important parameter that affects the efficacy of photodynamic therapy (PDT). However, the irregular morphologies of lesions complicate lesion segmentation and light irradiance adjustment. Therefore, this study developed an illumination demo system comprising a camera, a digital projector, and a computing unit to solve these problems. A three-dimensional model of a lesion w...