a rare case of diffuse lymphomatous polyposis of the gastrointestinal tract is reported in which the patient presented with abdominal pain, weight loss and bloody diarrhea. x-rays revealed multiple polyps involving the stomach, small intestine and colon. biopsies confirmed the diagnosis of lymphomatous polyposis. the duration of symptoms and signs was 3 months. diffuse lymphomatous polyposis of...

Mucosal injury caused by ischemia and reperfusion has been well documented with the small intestine, but little is known about the colon. In the present study, the effect of warm and cold ischemia on the canine colon was studied and compared to that on the small intestine. After in situ flushing, the small intestine and the colon from six beagle dogs were removed and stored for 0.5, 1.5, and 3 ...

Nowadays, various routes of administration have been explored for the effective delivery drug to target site. The oral route is considered be most convenient drugs patients. But it has a serious drawback in conditions where localized colon required. colon-targeted system (CDDS) potential approach systemic and topical treating inflammatory bowel diseases such as ulcerative colitis, Crohn’s disea...

Introduction: Computed tomography (CT) is an imaging technique with gives us an opportunity to review cross sections of the body in live animals. In veterinary medicine although CT is mostly used for diagnostic purposes in small animals, but in recent years CT also has been used as a non invasive modality in non clinical studies. Jebeer Gazelle (Gazella bennettii) is one of the species of the g...

The objective of this study was to develop a novel bacterially-triggered micro-particular system of de-esterified tragacanth (DET) in combination with Eudragit S-100 coated capsules for colon drug delivery of 5-fluorouracil (5-FU) using microemulsion method. The loading study was conducted at different drug-to-polymer ratios and cross-linker concentrations. The maximum loading efficiency was ac...

The objective of this study was to develop a novel bacterially-triggered micro-particular system of de-esterified tragacanth (DET) in combination with Eudragit S-100 coated capsules for colon drug delivery of 5-fluorouracil (5-FU) using microemulsion method. The loading study was conducted at different drug-to-polymer ratios and cross-linker concentrations. The maximum loading efficiency was ac...

   The aim of the present study was to develop a single unit, site-specific matrix tablets of aceclofenac allowing targeted drug release in the colon with a microbially degradable polymeric carrier, chondroitin suphate (CS) and to coat the optimized batches with a pH dependent polymeric. The tablets were prepared by wet granulation method using starch mucilage as a binding agent and HPMC K-100 ...

Short bowel syndrome (SBS) occurs when, after surgery or congenitally, a patient is left with 200 cm of functional small intestine. Absorption is related to the amount of residual intestine; patients at greatest nutritional risk generally have a duodenostomy or a jejunoileal anastomosis with 35 cm of residual small intestine, jejunocolic or ileocolic anastomosis with 60 cm of residual small int...

The aim of this study was to report a clinical case ileocaecal node in the visceral surgery department Donka. ileosigmoid or knot (ISK), is an exceptional entity, it surgical emergency characterized by strangulation small intestine forming around base sigmoid colon with risk rapid necrosis intestine. And colon. preoperative diagnosis condition difficult because its rarity and atypical radiograp...