Computational ligand screening is an approach to identify potential protein ligands efficiently using computational rather than experimental techniques. One approach is to test for the ability to identify and dock true ligands from a large number of molecular structures. Using this approach as implemented in our software SLIDE(1), screenings of 100,000-plus molecules can be achieved in a few ho...

In this paper, we propose a unified framework to address the problem of cytological computeraided diagnosis. Such an approach relies on our previously introduced formalisms: general formulation of discrete functional regularization, PDEs based morphology and geometric diffusion on graphs. The approach is illustrated through two applications in cytopathology, with examples of nucleus extraction ...

Background: Quantitative bacteriologic workup of BAL fluid (BALF) has evolved as a sensitive and specific technique for the diagnosis of bacterial pneumonia. Conventional quantitative cultures are expensive, time-consuming, and often unavailable on a 24-h basis. Therefore, we evaluated a dip slide method for the semiquantitative measurement of bacterial cultures in BALF specimens and com¬ pared...

[1] In this work, we study waves generated by the potential collapse of the west flank of the Cumbre Vieja Volcano (CVV; La Palma, Canary Island, Spain) through numerical simulations performed in two stages: (i) the initial slide motion and resulting free surface elevation are first calculated using a 3D Navier-Stokes model; (ii) generated waves are then input into a 2D (horizontal) Boussinesq ...

Attention control of audience is required for successful presentations, therefore giving a presentation with immediate reaction, called reactive presentation, to unexpected changes in the context given by the audience is important. Examples of functions for the reactive presentation are shape animation effects on slides and slide transition effects. Understanding the functions that realize th...

The paper is dedicated to the modeling of elasticity problem for a textile structure. made long and thin fibers, crossing each other in periodic pattern, forming woven canvas square domain. partially clamped. fibers cannot penetrate but can slide with respect in-plane directions. sliding bounded by contact function, which chosen loose. partial clamp loose lead domain partitioning, different exp...

Five commercial Staphylococcus aureus identification kits--Staphaurex (Wellcome), Staphylase (Oxoid), Staphyslide (bioMèrieux), Biostaph (Medlabs) and Bacto Latex (Difco)--were evaluated for the routine identification of S aureus from primary plates in the routine microbiology laboratory. Comparison was made with two methods of tube coagulase testing and five slide methods for detecting clumpin...