background: boron neutron capture therapy (bnct) is a radiotherapy that combines biological targeting and high linear energy transfer. a potential therapeutic approach for non-small cell lung cancer (nsclc) is considered. however, dose in lung tumor is not homogeneous, and it will reduce the effect of bnct treatment. in order to improve the dose distribution of bnct, the multi-field irradiation...

skin cancer has a broad and burdensome impact on the health and well-being of iranian and account for substantial health care costs to the nation. the first most common form of skin cancer is basal cell carcinoma (bcc); followed by the squamous cell carcinoma (scc) and the incidence of malignant melanoma (mm) is lower but is fatal. kaposi sarcoma (ks) is a tumor caused by human herpes virus 8. ...

Background and aim: Adult T cell leukemia/lymphoma (ATLL) is an aggresive malignancy which may occur in human T lymphotropic virus1(HTLV1) infected persons. HTLV1 is endemic in Khorasan with prevalence of 2.3% in general population. Since specific cutaneous manifestations of lymphoma may occur in a significant number of patients, we studied ATLL patients in Mashhad.Mate...

Background & Objective: This study was designed for the first time for the detection of mutant BRAF V600E and its correlation with clinicophathologic features in a sample of Iranian patients with pathologically proved pigmented skin neoplasms.Methods: 82 paraffin-embedded blocks, including melanocytic nevi, malignant melanoma, Basel cell carcinoma, and sq...

Introduction: Due to nuclear interactions between the tissues and high-energy protons, the particles, including neutrons, positrons, and photons arise during proton therapy. This study aimed at investigating the dose distribution of proton and secondary particles, such as positrons, neutrons, and photons using the Monte Carlo method. Material and Methods:<...

Mouse tumor models have undergone profound improvements in the fidelity of emulating human disease. Replacing ectopic s.c. implantation with organ-specific orthotopic implantation reproduces human tumor growth and metastasis. Strong fluorescent labeling with green fluorescent protein along with inexpensive video detectors, positioned externally to the mouse, allows the monitoring of details of ...