Diabetic muscular infarction (DMI) is a rare manifestation which can be seen in patients with long-standing diabetes mellitus. Patients usually come with painful swelling of an involved muscle in one extremity. MRI and biopsy histology can help diagnose this condition. Diabetic dermopathy is another manifestation of patients with diabetes.We present a patient with uncontrolled diabetes type 2 p...

The skin may exhibit the first clinical evidence of a systemic disease and may provide the first clues to a diagnosis in malignancies. Erythroderma is defined as generalized redness and scaling and it is a clinical manifestation of a variety of underlying diseases including, rarely, solid tumors. Breast cancer is associated with a variety of skin paraneoplastic manifestations like acanthosis ni...

Background: Waldenstrom macroglobulinemia is a lymphoplasmacytic lymphoma with elevated serum immunoglobulin M and multi-organ involvement. Primary systemic amyloidosis usually develops due to immunoglobulin light chains depositions in different organs due to an underlying gammopathy. Case presentation: Our patient was an 86-year-old man with macroglossia, ecchymotic patches and bullous lesion...

Thyroid dermopathy is an uncommon manifestation of autoimmune thyroid disease. About 0.5%-4.3% of patients with history of thyrotoxicosis and 15% of patients with severe Graves' ophthalmopathy have this cutaneous manifestation. However thyroid dermopathy is almost always associated with ophthalmopathy (96%) and sign and symptoms of hyperth-yroidism. The diagnosis of thyroid dermopathy is based ...

Rheumatoid Arthritis (RA) is a chronic systemic inflammatory disease which can involve tissues and organs other than the synovial joints. RA patients with skin manifestations usually have severe disease. Rheumatoid nodule is the most common skin manifestation seen in RA. Other skin conditions commonly described in RA are rheumatoid vasculitis, raynaud’s phenomenon and neutrophilic dermatoses. D...

Dermatomyositis, a connective tissue disorder, is an idiopathic inflammatory myopathy characterised by skin manifestation. The diagnosis of dermatomyositis based on rashes the skin, progressive muscle weakness, elevated serum enzymes, abnormal electromyogram, and findings biopsy. Hereby presenting this rare case 57-year-old female with all typical clinical interstitial lung disease.

Intuitively, dynamic visual stimuli, such as moving objects or flashing lights, attract attention. Visual search tasks have revealed that dynamic targets among static distractors can indeed efficiently guide attention. The present study shows that the reverse case, a static target among dynamic distractors, allows for relatively efficient selection in certain but not all cases. A static target ...

polyclonal anti-thymocyte globulin (atg) is used as an immunosuppressive agent in the treatment of aplastic anemia (aa). serum sickness is a recognized side effect of atg. we observed abnormal skin manifestation in patient with aplastic anemia who had been treated with atg. we conclude that abnormal immune function caused by aplastic anemia and atg and corticosteroids may aggravate the signs of...

The forehead plaque can be the earliest skin manifestation of tuberous sclerosis and its presence may lead to early diagnosis and appropriate genetic counselling.

Severe skin involvement complicated a case of sinus histiocytosis with massive lymphadenopathy in a young Malay girl. The clinical and histological features of this rare manifestation are described.