Introduction Immunoblast was the name proposed by Dameshek in 1963 to describe an antigenically "switched on" or transformed lymphocyte. Band T immunoblasts develop when the corresponding small resting lymphocyte is stimulated. The B immunoblasts further mature into plasma cells and both have been shown to produce antibodies after antigen stimulation• Lukes and CoIlins 4, by correlating immunol...

SIR, It has been suggested that HTLV-I infection may be associated with the development of some connective tissue diseases (CTD), including polyand dermatomyositis (PM and DM), systemic lupus erythematosus (SLE), scleroderma, and Sjogrens syndrome (SS).' 2 This was based on eight case reports in which neither the ethnic origin of their patients nor the assays used to determine HTLV-I seropositi...

DOS Times Vol. 12, No. 9 March, 2007 Endophthalmitis is one of the most vision threatening complication in Ophthalmology. Endophthalmitis refers to inflammatory response caused by infected intraocular tissues/ fluids. The frequency of Endophthalmitis after cataract surgery and trauma varies from 0.07 0.13% and 2.417% respectively in the various reported series.1 Majority of these infections are...

SIR, It has been suggested that HTLV-I infection may be associated with the development of some connective tissue diseases (CTD), including polyand dermatomyositis (PM and DM), systemic lupus erythematosus (SLE), scleroderma, and Sjogrens syndrome (SS).' 2 This was based on eight case reports in which neither the ethnic origin of their patients nor the assays used to determine HTLV-I seropositi...

SIR, It has been suggested that HTLV-I infection may be associated with the development of some connective tissue diseases (CTD), including polyand dermatomyositis (PM and DM), systemic lupus erythematosus (SLE), scleroderma, and Sjogrens syndrome (SS).' 2 This was based on eight case reports in which neither the ethnic origin of their patients nor the assays used to determine HTLV-I seropositi...

BACKGROUND Antibodies against Ro-52 have been described in patients with a broad spectrum of autoimmune disease, most commonly in association with anti-Ro-60 in systemic lupus erythematosus and Sjogrens syndrome. However, in inflammatory myositis anti-Ro-52 is frequently present without anti-Ro-60 and is closely linked to the presence of aminoacyl-tRNA synthetase (aats) antibodies. To date ther...