نتایج جستجو برای: singlet oxygen

تعداد نتایج: 218690  

Journal: :Molecules 2013
Xavier Ragàs Xin He Montserrat Agut Mónica Roxo-Rosa António Rocha Gonsalves Arménio C Serra Santi Nonell

Several families of photosensitizers are currently being scrutinized for antimicrobial photodynamic therapy applications. Differences in physical and photochemical properties can lead to different localization patterns as well as differences in singlet oxygen production and decay when the photosensitizers are taken up by bacterial cells. We have examined the production and fate of singlet oxyge...

2016
Ankush Prasad Ursula Ferretti Michaela Sedlářová Pavel Pospíšil

In the current study, singlet oxygen formation by lipid peroxidation induced by heat stress (40 °C) was studied in vivo in unicellular green alga Chlamydomonas reinhardtii. Primary and secondary oxidation products of lipid peroxidation, hydroperoxide and malondialdehyde, were generated under heat stress as detected using swallow-tailed perylene derivative fluorescence monitored by confocal lase...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 1986
T Hasan A U Khan

The spectroscopic observation of 1268-nm emission of singlet oxygen photosensitized by tetracyclines in oxygenated solutions at room temperature is reported. In the series demeclocycline, tetracycline, and minocycline, the efficiency of singlet oxygen generation is found to parallel the clinical observation of relative frequency of phototoxicity of these antibiotics, suggesting singlet oxygen g...

Journal: :Cancer research 1976
K R Weishaupt C J Gomer T J Dougherty

Singlet oxygen, a metastable state of normal triplet oxygen, has been identified as the cytotoxic agent that is probably responsible for in vitro inactivation of TA-3 mouse mammary carcinoma cells following incorporation of hematoporphyrin and exposure to red light. This photodynamic inactivation can be completely inhibited by intracellular 1,3-diphenylisobenzofuran. This very efficient singlet...

Journal: :Biochemistry 1965
R L HINMAN J LANG

The aerobic oxidation of indole-3-acetic acid catalyzed by horseradish peroxidase produces 1268 nm emission characteristic of singlet oxygen. Lactoperoxidase also oxidizes indole-3-acetic acid to produce singlet oxygen, but in contrast to horseradish peroxidase, this enzyme system requires hydrogen peroxide. In both of these systems, the intensity of the 1268 nm emission is small due to quenchi...

Journal: :Chemical communications 2009
Xavier Ragàs Ana Jiménez-Banzo David Sánchez-García Xavier Batllori Santi Nonell

The fluorescent probe Singlet Oxygen Sensor Green is able to produce singlet oxygen under exposure to UV or visible radiation.

2011
Defu Chen Huiyun Lin Yi Shen Zhiyi Liu Suihua Ma Yanhong Ji Huijuan Zhang Xiaojing Jiao Qianqian Chen Sisi Cui Haiyan Chen Yueqing Gu Yuanhao Tao Zhihua Ding Zhiyuan Shen Nan Zeng Yonghong He Bolin Hu

In this work, a near-infrared CCD-based singlet oxygen luminescence two-dimensional imaging method is proposed to detect singlet oxygen by its 1270nm luminescence. Two-dimensional singlet oxygen images with its near-infrared luminescence during photosensitization could be obtained with a CCD integration time of 1s, without scanning. The data presented shows a linear relationship between the sin...

Journal: :Chemical communications 2015
Gurusamy Saravanakumar Junseok Lee Jihoon Kim Won Jong Kim

Herein, we report a biocompatible amphiphilic block copolymer micelle bearing a singlet oxygen-sensitive vinyldithioether cleavable linker at the core-shell junction, which undergoes singlet oxygen-mediated photocleavage in the presence of visible light. The micelle facilitates the light-responsive release of singlet oxygen and an anticancer drug for enhanced photodynamic therapy.

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