OBJECTIVE To study the intrinsic fertility of the human oocyte. DESIGN A large retrospective study of natural cycle single embryo transfer (ET) IVF cycles. SETTING Private IVF clinic, university, and private hospital. PATIENT(S) Patients were enrolled consecutively over an 8-year period in a single ET natural cycle protocol. INTERVENTION(S) A total of 13,949 oocyte retrievals with natur...

BACKGROUND The most common complication of IVF is multiple pregnancy, which occurs in 25% of pregnancies following the transfer of two embryos. Single embryo transfer can minimize twin pregnancies but could also lower live birth rates. Our aim was to perform a systematic review of randomized trials to determine the effectiveness of single versus double embryo transfer. METHODS Cochrane Collab...

background: to compare the pregnancy outcomes after two embryos versus three embryos transfers (ets) in women undergoing in vitro fertilization (ivf)/intracytoplasmic sperm injection (icsi) cycles. materials and methods: this retrospective study was performed on three hundred eighty seven women with primary infertility and with at least one fresh embryo in good quality in order to transfer at e...

background: despite of higher pregnancy rate after frozen embryo transfer (fet) which is accepted by the majority of researches, the safety of this method and its effect on neonatal outcome is still under debate. objective: the aim of this study was to evaluate pregnancy and neonatal outcome of fet compare to fresh cycles. materials and methods: in this study,1134 patients using fresh et and 28...

Background: Vitrification and warming of blastocysts is an established procedure for the preservation of embryos during IVF. Vitrification is so successful that it allows for elective single embryo transfer (eSET) to be performed routinely, since the frozen embryos will be available with high implantation potential if the fresh embryo fails. Comprehensive chromosome screening (CCS) is also a pr...

BACKGROUND Reduction of the number of embryos transferred has been introduced to decrease the multiple birth rates (MBRs) after IVF and the associated risks for the children. The aim of this report is to present the effect of two steps in reduction of the number of embryos transferred, when applied in the majority of the patients, on national data for delivery and MBR after IVF in Sweden. MET...

BACKGROUND The aim of this study was to evaluate the impact of transferring a single top quality embryo in the first IVF/ICSI cycle of patients <38 years old who chose to have one or two embryos transferred. METHODS A total of 262 patients participated in the study, and 243 transfers were performed: 156 (64%) patients chose the transfer of a single top quality embryo, if available, and two no...

There has been an overall increase in the incidence of multiple pregnancies and assisted reproduction technology is largely responsible for this rise. Although twins may appeal to couples undergoing in vitro fertilisation (IVF), they have been associated with serious health consequences to the babies, their mothers and the family unit, as well as having massive financial implications for the Na...