This paper proposes a generalization of the nonlinear simultaneous equation model Pesaran and Pick (2007) by modelling comovement between two endogenous variables as smooth function magnitude variable rather than step function. The threshold speed at which shock is transmitted are estimated with other parameters model. We investigate properties an accurate estimation method takes into account e...

how to cite this article: taghdiri mm. other experimental therapies in neimann pick diseases. iran j child neurol. 2015 autumn;9:4(suppl.1): 25.   pls see pdf.

This paper deals with a routing problem variant which considers customers to simultaneously require delivery and pick-up services. The examined problem is referred to as the Vehicle Routing Problem with Simultaneous Pick-ups and Deliveries (VRPSPD). VRPSPD is an NP-hard combinatorial optimization problem, practical large-scale instances of which cannot be solved by exact solution methodologies ...

Vehicle Routing Problem with Simultaneous Pick-up and Delivery (VRP-SPD) is regarded as an NP-hard problem, which takes unacceptable time to use traditional algorithms to solve. This article presents an artificial immune systems or AIS-based algorithm to solve the problem and the results shows competitive performance. This algorithm is embedded with a sweep approach to generate random initial p...

The objective of this article is to present a new methodology for solving the Homogeneous Vehicle Routing Problem with Simultaneous Pickups and Deliveries (VRPSPD). integrates matheuristic using Chu-Beasley genetic algorithm mixed integer linear programming, based on Branch-and-Bound procedure. best configuration obtained from improved through use constructive heuristic methods in determining s...

An optimized design of a neutron detector based on timing RPCs (Resistive Plate Chambers) with boron-10 converters is presented. The composed stack ten double gap aluminium cathode plates coated both sides 10B4C. This enables simultaneous determination high accuracy the time-of-flight (down to ns resolution) and interaction position in 3D 0.25 mm resolution across ∼1 along beam). It shown that ...