Flavonolignans are the main components of silymarin, which represents 1.5-3% of the dry fruit weight of Milk thistle (Silybum marianum L. Gaernt.). In ancient Greece and Romania, physicians and herbalists used the Silybum marianum to treat a range of liver diseases. Besides their hepatoprotective action, silymarin flavonolignans have many other healthy properties, such as anti-platelet and anti...

Thistle oil (INCI: Silybum marianum seed oil) is known as an anti-oxidant, moisturizing and skin regenerating cosmetic raw material. Nanoemulsions are a new form of cosmetic product showing very good user properties (ease of spreading over the skin with no greasy feeling). Moreover, due to their structure, they can also transport both hydrophilic and hydrophobic active substances to the skin. T...

conclusions intake of water extract of silybum marianum is a useful treatment for liver function in drug-induced fatty liver. results concentrations of hdl-c and protein decreased and activity of alt increased in tmx group compared with the control group. the sme increased protein concentration and decreased alt activity in tmx-sme group compared with the tmx group. histopathological examinatio...

Chemotherapeutic agent, busulfan, induce oxidative stress as a mechanism to kill cancer cells, however, it may also cause in non-target tissues and thereby lead normal tissue injury. Milk thistle (Silybum marianum L.) has been used for centuries herbal drug. The present study was carried out investigate the potential effects of wild Silybum seed ethanol extract (SMSEE) intervention on induced b...

Diabetes mellitus is a public health problem which leads to serious complications over time. Experimentally, many herbs have been recommended for treating diabetes. In most cases, however, the recommendations are based on animal studies and limited pieces of evidence exist about their clinical usefulness. This review focused on the herbs, the hypoglycemic actions of which have been supported by...

background & aim: milk thistle [silybum marianum (l.) gaertn] is an annual or biennial plant, native to the mediterranean area, which has spread in north and south of iran. a fruit of milk thistle contains a relatively high amount (approx. 20%) of oil, which exhibits wound-healing, anti-burn, and hepatoprotective properties. experimental: in this research, a pot experiment was conducted usi...