نتایج جستجو برای: siah
تعداد نتایج: 275 فیلتر نتایج به سال:
Evaluation of Soil Moisture Changes Using the Balance Model in Zagros Oak Drying Forests (Case study: Melah Siah Forest - Ilam)
Kaposi's sarcoma-associated herpesvirus (KSHV), also referred to as human herpesvirus 8, is a potentially tumorigenic virus implicated in the etiology of Kaposi's sarcoma, primary effusion lymphoma, and some forms of multicentric Castleman's disease. The open reading frame 45 (ORF45) protein, encoded by the KSHV genome, is capable of inhibiting virus-dependent interferon induction and appears t...
The actualization of affordable housing remains a challenge. This challenge is exacerbated by the increasing societal demand for incorporation sustainability principles into such types to improve levels occupant health and well-being whilst avouching desired affordability. Innovative technologies practices have been described as beneficial effectuation sustainable housing. However, knowledge co...
The β-catenin functions as an adhesion molecule and a component of the Wnt signaling pathway. In the absence of the Wnt ligand, β-catenin is constantly phosphorylated, which designates it for degradation by the APC complex. This process is one of the key regulatory mechanisms of β-catenin. The level of β-catenin is also controlled by the E3 ubiquitin protein ligase SIAH-1 via a phosphorylation-...
Recent data demonstrate a structural and functional conservation of factors crucial for the development of the insect and the vertebrate eye. We isolated Xenopus siah-2, a protein with 67% identity to Drosophila sina (seven in absentia) and 85% identity to the mouse and human siah-2 proteins. Sina is required in Drosophila for the R7 photoreceptor cell formation during eye development, because ...
BACKGROUND Modelling moisture diffusivity of pomegranate cultivars is considered to be a major aspect of the drying process optimization. Its goal is mainly to apply the optimum drying method and conditions in which the final product meets the required standards. Temperature is the major parameter which affects the moisture diffusivity. This parameter is not equal for different cultivars of pom...
Aberrant activation of Wnt/ -catenin signaling and subsequent up-regulation of -catenin response transcription (CRT) is a critical event in the development of human colon cancer. Thus, Wnt/ -catenin signaling is an attractive target for the development of anticancer therapeutics. In this study, we identified hexachlorophene as an inhibitor of Wnt/ -catenin signaling from cell-based small-molecu...
Induction of a proinflammatory cytokine, interleukin-1β (IL-1β) plays a role in memory impairment associated with various neurological disorders and brain injury. Here we show that IL-1β-induced memory impairment in brain is mediated by hydrogen sulfide (H2S) synthesized by cystathionine beta-synthase (CBS). H2S modifies GAPDH essentially via sulfhydration in dendrites, which promotes its bindi...
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