نتایج جستجو برای: shv

تعداد نتایج: 1082  

Journal: :Antimicrobial agents and chemotherapy 2005
Dóra Szabó Melissa A Melan Andrea M Hujer Robert A Bonomo Kristine M Hujer Christopher R Bethel Katalin Kristóf David L Paterson

Bacteria that simultaneously produce multiple extended-spectrum beta-lactamases are frequently isolated. We report an Enterobacter cloacae isolate, ES24, producing four different beta-lactamases (AmpC type beta-lactamase, TEM-1, SHV-7, and a novel extended-spectrum beta-lactamase, SHV-30). Direct sequencing of bla(SHV) gene products gave a "double peak" at position 703, suggesting the presence ...

Journal: :Antimicrobial agents and chemotherapy 2005
Martina Zarnayová Eliane Siebor André Péchinot Jean-Marie Duez Helena Bujdáková Roger Labia Catherine Neuwirth

Eighty-five extended-spectrum beta-lactamase-producing Enterobacteriaceae from a Slovak hospital have been studied. SHV-2a was predominant, but other variants have been detected, namely, SHV-5, SHV-12, TEM-12, TEM-15, and TEM-132, which differed from TEM-1 by amino acid substitutions R164H, E240K, and I173V and had kinetic properties similar to those of TEM-28.

Journal: :Antimicrobial agents and chemotherapy 2007
Jodi M Thomson Fabio Prati Christopher R Bethel Robert A Bonomo

Boronic acid transition state inhibitors (BATSIs) with R1 side chains of cefotaxime and ceftazidime were assayed against SHV-1, SHV-2, SHV-5, D104K, and D104K G238S beta-lactamases. The D104K variant was the most susceptible to inhibition by the ceftazidime BATSI (Ki, 730+/-80 nM), while the D104K G238S variant was the most susceptible to the cefotaxime BATSI (Ki, 1.1+/-0.2 microM).

Journal: :Journal of chemotherapy 2005
B Bedenić H Schmidt S Herold M Monaco V Plecko S Kalenić S Katíc J Skrlin-Subić

Plasmid-encoded resistance to broad-spectrum cephalosporins and aztreonam is becoming a widespread phenomenon in clinical medicine. These antibiotics are inactivated by an array of different extended-spectrum beta-lactamases (ESBLs) which have evolved by point mutations of parental TEM or SHV beta-lactamases. In a previous study conducted during 1994-1995, SHV-2, SHV-2a and SHV-5 beta-lactamase...

2014
Varun Chandra Parijath N Goswami

Introduction: Extended-spectrum beta-lactamases (ESBLs) are rapidly evolving group of beta-lactamase enzymes commonly produced by the Gram negative bacteria, these enzymes have been derived from TEM and SHV genes by mutations. This study was done to look for TEM and SHV genes in ESBL positive E.coli and K. pneumoniae isolated from the cancer patients suffering with infections and admitted in a ...

Journal: :Antimicrobial agents and chemotherapy 2005
David S Hammond Jacqueline M Schooneveldt Graeme R Nimmo Flavia Huygens Philip M Giffard

Extended-spectrum beta-lactamases (ESBLs) emerge by point mutation from non-extended-spectrum precursors. The aims of this study were to reveal the basis for variations in resistance levels found in a collection of 21 Klebsiella pneumoniae clinical isolates from Brisbane, Australia. Previous studies have shown that 20 of these isolates possess bla(SHV-11), bla(SHV-2a), and/or bla(SHV-12), and t...

Journal: :The Journal of antimicrobial chemotherapy 1998
F H M'Zali J Heritage D M Gascoyne-Binzi A M Snelling P M Hawkey

The PCR single strand conformational polymorphism (PCR-SSCP) technique described to identify mutants of the SHV beta-lactamases was extended to identify an SHV-7 type beta-lactamase. This was found in a strain of Klebsiella pneumoniae, the first recorded isolate in the UK to produce this type of enzyme. We also demonstrate that PCR-SSCP can be used to identify more than one SHV beta-lactamase g...

Journal: :Infection and immunity 2008
Steve P Bernier David T Nguyen Pamela A Sokol

Burkholderia cenocepacia strain K56-2 typically has rough colony morphology on agar medium; however, shiny colony variants (shv) can appear spontaneously. These shv all had a minimum of 50% reduction in biomass formation and were generally avirulent in an alfalfa seedling infection model. Three shv-K56-2 S15, K56-2 S76, and K56-2 S86-were analyzed for virulence in a chronic agar bead model of r...

Journal: :Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi 2009
Selvi Palasubramaniam Sekaran Muniandy Parasakthi Navaratnam

BACKGROUND AND PURPOSE In addition to beta-lactamase production, loss of porins confers resistance to extended-spectrum beta-lactams in Klebsiella pneumoniae and Escherichia coli infection. This study describes the detection of SHV-12 extended-spectrum beta-lactamase (ESBL) subtype and the loss of OmpK35 porin in 4 strains of K. pneumoniae and E. coli. METHODS Isoelectric focusing was perform...

Journal: :World Journal Of Advanced Research and Reviews 2021

Background: The prevalence of ESBLs-producing Escherichia coli has recently increased worldwide due to the expression ESBL genes which had led high rate multidrug resistance antibiotics. Aim: To determine antimicrobial susceptibility patterns E. isolates and evaluating carriage these at phenotypic genotypic levels. Methods: One hundred two clinical were recovered from UTI suspects analyzed for ...

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