BACKGROUND Lead is one of the most toxic metals, producing severe organ damage in animals and humans. Oxidative stress is reported to play an important role in lead acetate-induced liver injury. AIM This study was carried out to investigate the role of ethanol extract of Eucheuma cottonii in protecting against lead acetate-induced hepatotoxicity in male mice. MATERIALS AND METHODS The sampl...

We studied the in-hospital prognosis of 1105 patients who had their first transmural myocardial infarction; 611 patients (55.3%) had anterior myocardial infarction (AMI) and 494 (44.7%) had inferior myocardial infarction (IMI). Patients with IMI had a significantly lower in-hospital mortality rate (9.1% vs 15.6%, p = 0.0014) and significantly lower prevalences of congestive heart failure (39.4%...

The present study was designed to investigate the antidiabetic activity of aqueous extract of Acacia tortilis polysaccharide (AEATP) from gum exudates and its role in comorbidities associated with diabetes in STZ-nicotinamide induced diabetic rats. Male albino Wistar rats were divided into control, diabetic control, glimepiride treated (10 mg/kg), and diabetic rats treated with 250, 500, and 10...

Dengue Haemorrhagic Fever (DHF) merupakan penyakit demam yang disebabkan oleh gigitan nyamuk Aedes aegypti dan albopictus. Terhitung sejak tahun 1968-2009, World Health Organization (WHO) mencatat negara Indonesia sebagai dengan kasus DHF tertinggi di Asia Tenggara menempati urutan kedua. Pasien penderita sering juga ditemukan adanya keterlibatan organ salah satunya adalah hepar. Virus penyebab...

BCG is an immune modulatory that inducing humoral and cellular immune responses during a number of infections including cutaneous leishmaniasis. Killed Leishmania Vaccine (KLV) has been applied for its immunogenicity in hosts. This study was carried out between 2010 and 2011 at the Department of Parasitology, Pasteur Institute of Iran. In the present study, alterations of Nitric Oxide (NO) leve...

Berberis aristata DC (Berberidaceae) is used in Indian traditional medicine. The hepatoprotective activity of Berberis aristata stem bark suspension was studied using CCl4 overdose induced liver damage in rats. The activity was assessed by monitoring various liver functions testing enzymes viz, Serum Glutamate Pyruvate transaminase (SGPT), Serum Glutamate Oxaloacetate Transaminase (SGOT), Serum...

Studies show that inhalation of oil gas vapor may impose serious health risks for individuals exposed to such vapor. The main aim of this study was to determine the effects of diesel oil vapor inhalation on SGOT and SGPT as indices of liver function. Male Wistar rats were randomly divided into control animals, and rats that exposed to diesel oil vapor for 1 hour/day, for 2 hours/day and for 3 h...

Ethanolic extracts of aerial parts of Solanum surattense burn. (SS), were subjected to in vivo study, by means of serum biochemical parameters and histopathological observations, in order to verify its traditional use in Hepatobiliary disorders. All groups of rabbits received a single dose of CCl4 subcutaneously on 7 th day except group I which was served as normal control . Group II served as ...