نتایج جستجو برای: sglt majorization

تعداد نتایج: 1707  

Journal: :Quantum Information & Computation 2001
Michael A. Nielsen Guifré Vidal

Majorization is a powerful, easy-to-use and exible tool which arises frequently in quantum mechanics as a consequence of fundamental connections between unitarity and the majorization relation. Entanglement theory does not escape from its in uence. Thus the interconversion of bipartite pure states by means of local manipulations turns out to be ruled to a great extend by majorization relations....

Journal: :Social Choice and Welfare 2014
Asis Kumar Banerjee

This paper considers the problem of constructing a multidimensional Lorenz dominance relation (MLDR) satisfying normatively acceptable conditions. One of the conditions, Comonotonizing Majorization (CM), is a weaker form of the condition of Correlation Increasing Majorizaton considered in the literature on multidimensional inequality indices. A condition, called Prioritization of Attributes und...

2017
Maria Lorenzi Uffe Jon Ploug Jakob Langer Rasmus Skovgaard Michael Zoratti Jeroen Jansen

INTRODUCTION For people with type 2 diabetes (T2DM) inadequately controlled with oral antidiabetic drugs (OADs), evidence from both randomized controlled trials (RCTs) and real-world studies has demonstrated that treatment intensification with liraglutide offers effective glycemic control, weight reduction, and a lower risk of hypoglycemia compared to treatment intensification with insulin or a...

2016
Masanori Wakisaka Tetsuhiko Nagao Mototaka Yoshinari

PURPOSE Mesangial cells play an important role in regulating glomerular filtration by altering their cellular tone. We report the presence of a sodium glucose cotransporter (SGLT) in rat mesangial cells. This study in rat mesangial cells aimed to evaluate the expression and role of SGLT2. METHODS The SGLT2 expression in rat mesangial cells was assessed by Western blotting and reverse transcri...

2017
Jiao Chen Fang Fan J. Y. Wang Yang Long C. L. Gao R. C. Stanton Yong Xu

To assess the efficacy and safety of the SGLT-2 inhibitors as adjunct therapy to insulin in T1DM, clinical trials indexed in PubMed, Cochrane Library, EMbase from inception through April 5, 2016. A meta-analysis was conducted on trials of SGLT-2 inhibitors in patients with T1DM on insulin therapy using RevMan 5.3 software. Of the 371 articles identified, ten met eligibility criteria. Seven clin...

Journal: :American journal of physiology. Regulatory, integrative and comparative physiology 2001
M C De La Horra M Cano M J Peral M L Calonge A A Ilundáin

The effects of aldosterone and arginine vasotocin (AVT) on intestinal Na(+)/H(+) exchange (NHE) and Na(+)-sugar cotransport (SGLT-1) activities have been investigated using brush-border membrane vesicles isolated from Hubbard chicken small and large intestines, and they were compared with those induced by either Na(+) depletion or dehydration. Na(+) depletion was induced by feeding the chickens...

Journal: :American journal of physiology. Regulatory, integrative and comparative physiology 2006
Thorsten Althoff Hartmut Hentschel Jutta Luig Hendrike Schütz Myriam Kasch Rolf K-H Kinne

Using primers against conserved regions of mammalian Na(+)-d-glucose cotransporters (SGLT), a cDNA was cloned from the kidney of spiny dogfish shark (Squalus acanthias). On the basis of comparison of amino acid sequence, membrane topology, and putative glycosylation and phosphorylation sites, the cDNA could be shown to belong to the family of sglt genes. Indeed, Na(+)-dependent d-glucose uptake...

2009
Ulrik Brandes Christian Pich

We describe an algorithm for radial layout of undirected graphs, in which nodes are constrained to the circumferences of a set of concentric circles around the origin. Such constraints frequently occur in the layout of social or policy networks, when structural centrality is mapped to geometric centrality, or when the primary intention of the layout is the display of the vicinity of a distingui...

2017
Yuji Aoki Masato Aoki David JA Jenkins

It is known that plasma (serum) vitamin C level is lowered in diabetic patients by some mechanisms including renal loss [1]. Vitamin C and glucose filtered from the glomerulus are presumed to be reabsorbed at the renal proximal tubule by sodium-vitamin C co-transporter (SVCT) 1 and sodium-glucose co-transporter (SGLT) 2, respectively [2-4]. In the enterocyte that expresses SVCT 1 and SGLT 1, it...

Journal: :Molecules 2017
Huizhen Cai Xiaohui Yang Qian Cai Binbin Ren Hongyan Qiu Zhiqing Yao

Lycium barbarum L. polysaccharide (LBP) is prepared from Lycium barbarum L. (L. barbarum), which is a traditional Chinese medicine. LPB has been shown to have hypoglycemic effects. In order to gain some mechanistic insights on the hypoglycemic effects of LBP, we investigated the uptake of LBP and its effect on glucose absorption in the human intestinal epithelial cell line Caco2 cell. The uptak...

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