Leydig cell tumors are rare testicular tumors of the male gonadal interstitium. Although uncommon, Leydig cell testicular neoplasms are the most common sex cord-stromal tumors and comprise 1-3% of all testicular neoplasms. This tumor is always benign in children and approximately 90% are benign in adults. In most cases, patients present with an incidental finding of a testicular mass on scrotal...

Non-epithelial malignancies of the ovary account for 10% of all ovarian cancers. Germ cell tumors (GCTs) are diagnosed principally in young subjects whereas sex cord stromal tumors (SCSTs) are more common in adult women. GCTs represent 5% of all ovarian neoplasms and 80% of preadolescent malignant ovarian tumors. Sex cord stromal tumors are rare neoplasms that account for 3–5 % of ovarian malig...

background: recent studies have showed conservative management in selective patients with borderline and malignant ovarian tumors is safe; therefore this management is considered in patients with ovarian tumor who desire to preserve fertility. objective: this study has been performed to evaluate the clinical outcome and fertility in patients with ovarian tumors who were treated conservatively. ...

Gonadoblastoma is a rare gonadal tumour consisting of a mixture of germ cells and sex cord stromal derivatives resembling immature granulosa and Sertoli cells. It usually arises in various types of gonadal dysgenesis containing Y chromosome like pure or mixed gonadal dysgenesis. Occurrence in phenotypically and chromosomally normal women is very rare. We report here a case of gonadoblastoma wit...

OBJECTIVE The majority of ovarian tumors in girls and young women are nonepithelial in origin. The etiology of nonepithelial ovarian tumors remains largely unknown, and intrauterine exposures may play an important role. We examined the association of perinatal factors with risk of nonepithelial ovarian tumors in girls and young women. METHODS National cohort study of 1,536,057 women born in S...

Uterine tumors resembling ovarian sex cord tumors (UTROSCTs) are a rare group of stromal neoplasms containing prominent sex cord-like elements. Since they were first described in 1945 by Morehead and Bowman [1], no more than 100 such tumors have been reported [2]. In a report by Clement and Scully [3], these neoplasms were divided into 2 groups on the basis of clinical and histologic patterns. ...

OBJECTIVES The sex cord stromal tumors (SCST) account for approximately 7% of all malignant ovarian tumors. They are endocrinologically active tumors of which granulosa cell tumors are the commonest. We describe an analysis of all cases of SCST managed, in our department over the last five years and discuss two cases of unusual presentation of these tumors. METHODS Ten cases of SCST which wer...

Testicular fibroma of gonadal stromal origin is a rare benign tumor of testis which usually presents as a slow growing testicular mass. Only 25 cases of testicular fibroma have been reported in the literature. Presence of minor sex cord elements in this tumor is even rarer. We report a case of testicular fibroma with minor sex cord elements that involved almost the entire testis and tunica vagi...

Endometrial stromal tumors are reviewed with emphasis on their wide morphologic spectrum and problems in differential diagnosis, highlighting issues that have received particular attention in the recent literature. These neoplasms are divided into two major categories--endometrial stromal nodules and endometrial stromal sarcomas--a distinction made on the basis of the lack of significant infilt...