نتایج جستجو برای: severe diffuse axonal injury
تعداد نتایج: 692334 فیلتر نتایج به سال:
The accumulation of myelin debris may be a major contributor to the inflammatory response after diffuse axonal injury. In this study, we examined the accumulation and clearance of myelin debris in a rat model of diffuse axonal injury. Oil Red O staining was performed on sections from the cerebral cortex, hippocampus and brain stem to identify the myelin debris. Seven days after diffuse axonal i...
Traumatic brain injury is a nondegenerative, noncongenital insult to the brain caused by external mechanical forces. Recent studies suggest that even mild concussions—if repetitive—can trigger progressive neurological degeneration, a condition that is now widely known as ‘‘chronic traumatic encephalopathy’’ (1). Notably, chronic traumatic encephalopathy continues to progress even decades after ...
We demonstrate that in head injuries the degree of cerebral endothelial activation or injury depends on the type of brain injury and the patients age, and that in severe head injuries measuring the serum levels of thrombomodulin (TM) and von Willebrand factor (vWF) is useful in evaluating cerebral endothelial injury and activation. The values of vWF in the cases of focal brain injury were signi...
To address the relationships of clinical symptoms and pathology and the location and magnitude of brain strains, the Wayne State University human head finite element model was used with loading conditions posited to produce severe concussion (AIS 3) and mild, moderate and severe diffuse axonal injury (DAI) (AIS 4 ‐ AIS 5). Sinusoidal accelerations with peak thresholds of 8,100, 11,000, 14,00...
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