The study of serum transaminases has recently entered clinical practice. In December, 1954, Wroblewsky and La Due demonstrated an increase of glutamic-oxalacetic (GOT) transaminase in the serum of patients suffering from various liver diseases and in carbon tetrachloride intoxication. In 1955, de Ritis, Coltorti and Giusti demonstrated an increase of both aspartic-ketoglutaric (GOT) and alanine...

The results obtained in the present investigations point to a definite correlation between the onset of myocardial injury, electrocardiographic changes and biochemical changes. Changes in the electrocardiogram and elevated serum levels were paralleled by an increased excretion of magnesium in urine as early as one hour. Serum calcium and serum potassium levels did not show any significant ...

 Background and rationale. Nonalcoholic fatty liver disease (NAFLD) is the most common cause of pediatric liver disease in western countries. Its prevalence in Indian subcontinent is not well studied. MATERIAL AND METHODS In a school based cross sectional study we have screened overweight and obese children in the age group of 11 to 15 years for NAFLD. Ultrasonography, elevated serum transami...

Recently assays of glycolytic enzymes and transaminases have significantly expanded the diagnostic possibilities of internal medicine. Thus one may confirm myocardial infarction by serum transaminase activity within the first few hours in at least 95 per cent. of all cases. The testing of these enzymes has also improved the diagnosis of virus hepatitis and other liver diseases, and their undoub...

In 33 methyl bromide users, slight electroencephalographic changes (in 10 subjects) and a small increase in serum transaminases were found which could be related to bromine concentration in blood. No relationship was found with subjective symptoms, general neurological examination or the results of serum protein electrophoresis.

Serum transaminases were determined according to the method ofKarmen, Wrobleski, and LaDue (1955) (normal values for our laboratory: SGOT and SGPT up to 15 i.u./ litre), serum salicylate levels with Trinder's reagent, fibrinogen according to the method of Clauss (1957), fibrinogen degradation products (FDP) by the immunodiffusion technique (Ouchterlony), and Factor V according to the method of ...