objective(s):the aim of the study was to investigate the relationship between insulin resistance (ir) and leptin (lep) gene polymorphisms in peritoneal dialysis (pd) patients. materials and methods: from july 1, 2011 to august 1, 2011, patients who received chronic pd were chosen and divided into three groups (dm, high homr-ir, and low homr-ir). two pcr products of lep were sequenced and aligne...

The article contains the analysis of results concerning investigation adipocytokines content and endothelial dysfunction in 97 patients with irritable bowel syndrome associated obesity. blood serum was examined for (leptin, adiponectin, resistin), stable nitrogen monoxide metabolites (nitrites/nitrates), endothelin-1, intercellular adhesion molecule 1 (ICAM-1), number circulating cells (CEC). P...

objective: serum leptin concentration reflects the body fat mass. there is controversial reports about the insulin effect on serum leptin concentration. we wanted to examine the effect of insulin therapy on serum leptin in children with new onset type i diabetes. materials and methods: this was a cross-sectional study in children's medical center on 34 children who had new onset type i dia...

Background: The prevalence of non-alcoholic fatty liver disease is higher in patients with psoriasis than in the normal population. Serum leptin levels are higher in patients with psoriasis and in patients with non-alcoholic fatty liver. The purpose of this study was to determine the serum levels of leptin in psoriatic patients with and without non-alcoholic fatty liver.<span...

Background: Leptin and its receptors have been found in the human gastric mucosa.  Its secretion by gastric mucosa has generated interest in its probable role in the gastrointestinal tract and pathophysiology of diseases. Objective: To determine any possible correlation between serum leptin level and pathological findings in patients with duodenal ulcer (DU). Methods: In a cross-sectional study...

Background: Oxidative stress in obese people is an important pathogenic mechanism of an obesity-associated metabolic syndrome. We evaluated the association between circulating leptin levels with biomarkers of oxidative stress in overweight and obese participants. &nbsp;&nbsp; Methods: This study was performed on 189 overweight and obese people aged 18-60 years old. Serum leptin, superoxide dis...

background: leptin has been implicated in the differentiation and proliferation of hematopoietic cells. leukemia inhibitory factor (lif) may play an important role, along with interleukin-6 (il-6) and granulocyte colony stimulating factor (g- csf), in the regulation of early hematopoietic stem cells. the aim of the study was to evaluate serum level of leptin, lif, and il-6 in myeloid leukemia p...