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Background & Aim: This study evaluated prevention effect of hydro-alcoholic extract of punica granatum Peel ethylene glycol-induced Nephrolithiasis in wistar rats. Experimental: 20 male Wistar rats were randomly divided into 4 equal groups. Group I animals served as normal control (A) and received distilled water for 28 days. Group II to IV animals received 1% v/v ethylene glycol (EG) in disti...
objective: the clinical use of cisplatin is highly restricted, because of its nephrotoxicity.in this study the protective effect of nigella sativa (n. sativa) against cisplatin-induced nephrotoxicity was investigated in rats. materials and methods: in the current study, the effects of the administration of aqueous-ethanolic extract of n. sativa (100 and 200 mg/kg, bw) and vitamin e (100 mg/kg, ...
Thirty-seven young healthy subjects with normal renal function were studied to assess the quantitative effect of protein intake on creatinine clearance. A standard 24-h urine collection and blood sample at the end of the collection were obtained for creatinine and urea concentrations. Correlations between creatinine clearance and urinary urea nitrogen excretion (r = 0.8; P less than 0.0001) and...
Background: Preterm birth occurs in a large number of pregnancies, and its incidence has been reported to be on the rise. Acute kidney injury (AKI) is a common complication in the premature infants with respiratory distress syndrome (RDS). The present study aimed to determine the predictive factors, clinical courses, and outcomes of AKI in the neonates with the clinical and radiological manifes...
seventy six high and low producer cows were selected to determine the composition of theblood and milk parameters, and their interrelationships to determine the indices which could beuseful to improve the milk yield. the highest mean blood concentrations were found in highproducer cows. mean values for blood urea nitrogen (bun), serum protein (sptn), creatinine,triglycerides (tgs), cholesterol,...
BACKGROUND AND THE PURPOSE OF THE STUDY The combination of angiotensin II receptor antagonists and HMG CoA reductase inhibitors have shown to confer renoprotection.The purpose of this study was to find out the renoprotective effects of telmisartan and atorvastatin in combination and in monotherapy of Streptozotocin (STZ) induced diabetic nephropathy in rats. METHODS Diabetes was induced by i....
The diagnosis of acute kidney injury (AKI) is usually based on measurements of blood urea nitrogen (BUN) and serum creatinine. BUN and serum creatinine are not very sensitive or specific for the diagnosis of AKI because they are affected by many renal and nonrenal factors that are independent of kidney injury or kidney function. Biomarkers of AKI that are made predominantly by the injured kidne...
Objective: The clinical use of cisplatin is highly restricted, because of its nephrotoxicity.In this study the protective effect of Nigella sativa (N. sativa) against cisplatin-induced nephrotoxicity was investigated in rats. Materials and Methods: In the current study, the effects of the administration of aqueous-ethanolic extract of N. sativa (100 and 200 mg/kg, BW) and vitamin E (100 mg/kg, ...
background & aim: punica granatum l. (pomegranate) is a widely used plant that has high nutritional value .this study evaluated prevention effect of hydro alcoholic extract of punica granatum flower and leaves ethylene glycol-induced nephrolithiasis in wistar rats. experimental: 20 male wistar rats were randomly divided into 4 equal groups. group i served as positive control and received distil...
Background and Aims: Bisphenol A (BPA) falls in the category of hormonal disruptors due to its widespread application, and several studies have revealed its toxicity in different doses. However, few studies have investigated the effect of BPA on the renal system. Therefore, the present study aimed to investigate the effect of BPA on renal system function in rats. Materials and Methods: Initial...
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