Saddle blockade with pethidine hydrochloride was performed in 111 patients undergoing short surgical operations on the perineum. A dose of 5% pethidine 0.5 mg kg-1 was injected to the subarachnoid space at L4-5 or L5-S1 with the patient in the sitting position. Sensory blockade was achieved in 5.28 +/- 1.43 min. This extended to the sacrococcygeal area, perineum, buttocks and posterior surface ...

: Several drugs and drug regimens are used as adjuncts to local anaesthetics for neuraxial blockade in order enhance its efficacy. In recent times novel drugs, adrenergic agonists like dexmedetomidine clonidine extensively used. Very few studies have compared the equipotent doses of both when given pre-emptive analgesia. This study compares efficacy intravenous prolongation bupivacaine spinal a...

background: after spinal anesthesia, patients undergoing cesarean section are more likely to develop hemodynamic changes. the baricity of local anesthetic has an important role on spinal blockade effects. the aim of this study was to compare the isobar and hyperbaric bupivacaine 0.5% plus fentanyl on maternal hemodynamics after spinal anesthesia for c/s. methods: in this double-blind study, 84 ...

Background: After spinal anesthesia, patients undergoing cesarean section are more likely to develop hemodynamic changes. The baricity of local anesthetic has an important role on spinal blockade effects. The aim of this study was to compare the isobar and hyperbaric bupivacaine 0.5% plus fentanyl on maternal hemodynamics after spinal anesthesia for C/S.Methods: In this double-blind study, 84 h...

Various drugs have been used as epidural adjuvants to enhance the quality and duration of surgical anaesthesia. We aimed at evaluating the effects of Neostigmine, an acetylcholine esterase inhibitor, as an adjuvant to epidural anaesthesia with 0.5% Bupivacaine for vaginal hysterectomy. In this clinical comparative randomized study, 60 ASA I & II patients requiring vaginal hysterectomy were rand...

BACKGROUND The authors compared the efficacy of the different approaches to saphenous nerve block. METHODS The following approaches to saphenous nerve block were compared in 10 volunteers: perifemoral, transsartorial, block at the medial femoral condyle, below-the-knee field block, and blockade at the level of the medial malleolus. Each volunteer underwent all five blocks, and the interval be...

An increase in the concentration of bupivacaine from 0.5% to 0.75% and etidocaine from 1.0% to 1.5% for extradural block resulted in a more rapid onset of sensory analgesia and motor blockade, a greater frequency of adequate analgesia,a greater depth of motor block and a longer duration of sensory analgesia and motor blockade. An increase in the concentration of prilocaine from 2% to 3% failed ...

CONTEXT AND OBJECTIVES In major orthopedic surgery of the lower limbs, continuous spinal anesthesia (CSA) and combined spinal epidural anesthesia (CSE) are safe and reliable anesthesia methods. In this prospective randomized clinical study, the blockading properties and side effects of CSA were compared with single interspace CSE, among patients scheduled for major hip or knee surgery. DESIGN...

Background: Ultrasound continues to grow in popularity as a method of nerve localization and it has the advantage of allowing real time visualization of the plexus , pleura and vessels along with the needle and local anaesthetic spread. [4] So this study intends to compare efficacy and safety of Inj.clonidine and Inj.Dexmedetomidine as adjuvant to local anaesthetic for USG guided subclavian per...