BACKGROUND Apple allergy manifests as two main groups of clinical entities reflecting different patterns of allergen sensitization: oral allergy syndrome (OAS) and generalized symptoms (GS). OBJECTIVE We analysed the sensitization profile to a wide panel of different components of food allergens (rMal d 1, Mal d 2, rMal d 3, rMal d 4, rPru p 3, rBet v 1 and Pho d 2) for a population of Medite...

BACKGROUND The relationship between sensitization to allergens and disease is complex. OBJECTIVE We sought to identify patterns of response to a broad range of allergen components and investigate associations with asthma, eczema, and hay fever. METHODS Serum specific IgE levels to 112 allergen components were measured by using a multiplex array (Immuno Solid-phase Allergen Chip) in a popula...

Lipid transfer protein (LTP) is a major allergen in peach often causing anaphylactic reactions with a high prevalence of sensitization in the Mediterranean area. The prevalence of LTP sensitization in Central Europe is currently unknown, where the diagnosis is complicated by a high background sensitization to the major birch pollen allergen, Bet v 1, and Bet v 1 cross-reactive food allergens, w...

Background Sensitization to cat and/or dog allergens during childhood represents a risk factor for the development of allergic diseases later in life. Objective The study investigated association patterns sensitization and allergen components with clinical symptoms allergy these furry animals among cat-sensitized children. Methods children were evaluated presence bronchial asthma, atopic dermat...

BACKGROUND Early life rhinovirus (RV) wheezing illnesses and aeroallergen sensitization increase the risk of asthma at school age. Whether these remain risk factors for the persistence of asthma out to adolescence is not established. OBJECTIVE We sought to define the relationships among specific viral illnesses and the type and timing of aeroallergen sensitization with the persistence of asth...

the catastrophic effects of opioids use on public health and the economy are documented clearly in numerous studies. repeated morphine administration can lead to either a decrease (tolerance) or an increase (sensitization) in its behavioral and rewarding effects. morphine-induced sensitization is a major problem and plays an important role in abuse of the opioid drugs. studies reported that mor...

BACKGROUND Immune responses in allergic diseases begin with allergen sensitization, which usually occurs in childhood. Allergen sensitization involves a complex interplay of genetic and environmental factors, and sensitization patterns may change with age. OBJECTIVE To determine the predictors of allergen sensitization in the first 3 years of life in the growing up in Singapore towards health...

The question of addiction specifically concerns (1), the process by which drug-taking behavior, in certain individuals, evolves into compulsive patterns of drug-seeking and drug-taking behavior that take place at the expense of most other activities and (2), the inability to cease drug-taking; the problem of relapse. In this paper current biopsychological views of addiction are critically evalu...