Inonotus obliquus is a medicinal mushroom used in Russian and Eastern European folk medicine for the treatment of gastrointestinal cancer, cardiovascular disease and diabetes. Previous studies in our laboratory have demonstrated that the mycelium powders of I. obliquus possess significant antihyperglycemic effects in a mouse model of diabetic disease induced by alloxan. However, the active ingr...

Isothermal and non-isothermal torrefaction characteristics and kinetics of microalga Scenedesmus obliquus (S. obliquus) CNW-N are studied using thermogravimetric analysis. The pyrolysis of S. obliquus CNW-N with increasing temperature is characterized by four-stage decomposition. Depending on the torrefaction temperature, light, mild, and severe torrefaction from the weight loss and the maximum...

The medicinal macrofungus Inonotus obliquus widely utilized as folk medicine in Russia and Baltic countries is a source of phenylpropanoid-derived styrylpyrone polyphenols that can inhibit tumor proliferation. Insights into the regulatory machinery that controls I. obliquus styrylpyrone polyphenol biosynthesis will enable strategies to increase the production of these molecules. Here we show th...

The activity of seven trunk muscles was recorded at two sites along the trunk in adult spotted salamander, Ambystoma maculatum, during swimming and during trotting in water and on land. Several muscles showed patterns of activation that are consistent with the muscles producing a traveling wave of lateral bending during swimming and a standing wave of bending during aquatic and terrestrial trot...

Hydrogen evolution is observed in the green alga Scenedesmus obliquus after a phase of anaerobic adaptation. In this study we report the biochemical and genetical characterization of a new type of Fe-hydrogenase (HydA) in this photosynthetic organism. The monomeric enzyme has a molecular mass of 44.5 kDa. The complete hydA cDNA of 2609 bp comprises an open reading frame encoding a polypeptide o...

BACKGROUND To investigate the antitumor effect of Inonotus obliquus Pilat, the antiproliferative effect of lanostane triterpenoids from a chloroform extract of I. obliquus sclerotia against mouse leukemia P388 cells was assessed. MATERIALS AND METHODS Cell viability was measured by MTT assay. Caspase-3/7 activity and DNA fragmentation were evaluated to analyze apoptosis induction. The in vivo...

Understanding the functional role of the cervical muscles is important for the effective diagnosis and treatment of cervical disorders. The suboccipital muscles are targets for treatment in whiplash and chronic headache, although their function remains unclear. There are no data on suboccipital muscle fiber type composition to facilitate an understanding of their function. Suboccipital muscles ...

Nano-Al₂O₃ has been widely used in various industries; unfortunately, it can be released into the aquatic environment. Although nano-Al₂O₃ is believed to be of low toxicity, it can interact with other pollutants in water, such as heavy metals. However, the interactions between nano-Al₂O₃ and heavy metals as well as the effect of nano-Al₂O₃ on the toxicity of the metals have been rarely investig...

Two freshwater and two marine alg;tl species were grown in intensive contiimous cultures at a fixed dilution rate of 0.5 ·day -I, but at varying pH levels in the range 7.6 to 1C.6. Both freshwater species, Scenedesmus obliquus (Turp.) Kutz. and Chlorella vulgaris Beij., grew up to pH 10.6 although C. vulgaris was more adversely affected by alkaline pH than was Scenedesmus obliquus. Of the marin...

Subcritical water extraction (SWE) of Inonotus Obliquus polysaccharides (IOP) was investigated using response surface methodology (RSM) with a design by Box–Behnken design (BBD). Results showed that the optimum SWE conditions for IOP production were as follows: extraction temperature 194°C, residence time 5.36 min and liquidsolid ratio 53 mL/g, yielding 168.80 ± 0.59 mg/g of IOP, which was in c...