background: sensitive and glucantime (ma) resistance leishmania tropica are referred to those isolates, which are responsive, or non-responsive to one or two full courses of treatment by ma systematically and/or intra-lesionally, respectively. in this study, we evaluated the antileishmanial activity of biogenic selenium nanoparticles (se nps) alone and in combination with ma against sensitive a...

We present, for the first time, versatile solutions of concentrated selenium, within an array of amines, in a fast and low temperature manner without contaminants. These solutions allow the unprecedented opportunity to synthesize a variety of pure selenium and selenide nanoparticles as well as mixed chalcogen sulfoselenide compounds.

Shewanella sp. HN-41 was exploited for selenium nanoparticles synthesis from aqueous selenite compounds under anaerobic conditions. Various reaction conditions, including reaction time, initial biomass, and initial selenite concentration, were systematically investigated to determine their effects on particle size distribution and formation rate. The biomass concentration of Shewanella sp. HN-4...

Selenium (Se) is an essential element with a small difference between physiological and toxic doses. To provide more effective and safe Se dosing regimens, as compared to dosing with ionic selenium, nanoparticle formulations have been developed. However, due to the nano-formulation, unexpected toxic effects may occur. We used metabolite pattern determination in urine to investigate biological a...

BACKGROUND Nanotechnology has enabled researchers to synthesize nanosize particles that possess increased surface areas. Compared to conventional microparticles, it has resulted in increased interactions with biological targets. OBJECTIVE The objective of this study was to determine the protective ability of selenium nanoparticles against hexavalent chromium-induced thyrotoxicity. DESIGN Tw...

First selenium ligand stabilized Pd(0) nanoparticles (∼3-5 nm) catalyze Suzuki-Miyaura C-C coupling in short time and are recyclable (up to 94% yield after 5 reuses). The air stable compound [PdCl(2)(L1)(2)] shows high catalytic efficiency for this coupling as its 3 × 10(-5) mol% is sufficient for activated ArBr.

Introduction: Diabetes mellitus, as a chronic metabolic disease, is associated with a wide range of kidney and liver disorders. The goal of this study was to indicate the effects of selenium nanoparticles on the function of kidney and liver enzymes in stereptozocin induced diabetic rats. Methods: In this study, 35 male wistar rats were divided into five groups (n=7): control, diabetic control a...

The aim of the present study was to investigate the interaction of zinc chloride (3 mg/kg, intraperitoneally [ip]) in rat liver in terms of the biosynthesis of nanoparticles. Zinc treatment increased zinc content in rat liver. Analysis of fluorescence revealed the presence of red fluorescence in the liver following zinc treatment. Interestingly, the co-exposure to zinc (3 mg/kg, ip) and seleniu...

The present study was (i) to prepare two types of selenium nanoparticles, namely an amorphous form of selenium quantum dots (A-SeQDs) and a crystalline form of selenium quantum dots (C-SeQDs); and (ii) to investigate the nano-bio interactions of A-SeQDs and C-SeQDs in MCF-7, HepG2, HeLa, NIH/3T3, L929 cells and BRL-3A cells. It was found that A-SeQDs could induce the mitochondria-mediated apopt...