Relevant and timely questions such as regarding the predictability of seizures and their capacity to trigger more seizures remain the subject of debate in epileptology. The present study endeavors to gain insight into these dynamic issues by adopting a non-reductionist approach and via the use of mathematical tools. Probability distribution functions of seizure energies and inter-seizure interv...

x CHAPTER I GENERAL INTRODUCTION 1 Seizures in Man 1 Occurrence 1 Etiology 1 Animal Models of Convulsive Disorders 4 Seizure Models Based on Electrical Stimulation ... 5 Seizure Models Based on Chemical Stimulation .... 7 Seizure Models Based on Cortical Lesions 7 Seizure Models Based on Genetic Determinants .... 8 Putative Neuromediators in Seizure Activity 10 Catecholamines 10 5-Hydroxytrypta...

Background and Objective: Some neurologic complications may be detected after renal transplantation in children including tremor, peripheral neuropathy, altered level of consciousness and seizure. The aim of our study was to detect the prevalence of seizure after renal transplantation and its risk factors in pediatric age groups. Methods: In this descriptive study, 102 patients 5-14 yea...

A 3-year-old female pug presented with general seizure following a partial seizure. During the remaining 48 months till death, the dog showed various neurological signs such as disturbance of consciousness, myoclonus and various types of partial seizure after each occurrence of the seizure clusters, and the dog eventually exhibited inability to stand and dementia. Magnetic resonance imaging fin...

Background: Storage of platelet concentrates (PCs) at room temperature (20-24°C) limits its storage time to 5 Background: Glucose-6-phosphate dehydrogenase (G6PD) deficiency is the most common inherited enzyme deficiency of the human red blood cells . Most of G6PD deficient individuals are asymptomatic, but acute hemolytic anemia may be presented with nausea, vomiting, abdominal pain, headache,...

Previous work has shown that medication errors related to anticonvulsants are common during the transition into the hospital for pediatric patients. The purpose of this work was to evaluate whether children with epilepsy admitted for reasons other than epilepsy experience nonoptimal care in anticonvulsant medication management preceding the occurrence of seizures. Using a retrospective cohort o...

background and objective: some neurologic complications may be detected after renal transplantation in children including tremor, peripheral neuropathy, altered level of consciousness and seizure. the aim of our study was to detect the prevalence of seizure after renal transplantation and its risk factors in pediatric age groups. methods: in this descriptive study, 102 patients 5-14 year old in...

IntroductionSpontaneous intracerebral haemorrhage (ICH) is associated with high mortality and morbidity, including seizures. Seizure prophylaxis “not recommended” by the American Stroke Association, but practice variation still exists due to inconclusive data. We performed a meta-analysis assess current relevant literature determine efficacy of seizure following ICH.MethodsWe searches PubMed, S...

We carried out a Hungarian multicentre study to assess the frequency of the occurrence of warning symptoms preceding epileptic seizure. The data of 562 patients with epilepsy out of a total of 1124 were analysed on the basis of questionnaires filled in under standard conditions. About 50% of the patients experienced warning symptoms before a smaller or greater part of their seizures. Their appe...

PURPOSE To evaluate the 1-year efficacy and safety of oral lacosamide as conversion monotherapy in adult patients with partial onset seizures with or without generalization. METHOD We prospectively followed-up consecutive patients converted to lacosamide monotherapy after 1-year seizure freedom on lacosamide add-on therapy and withdrawal of the concurrent antiepileptic drug (AED). Seizure occ...