in recent years, ionic liquids have been used in pharmaceutical processes. therefore, having a deep insight into the ion association behavior of ionic liquids in the presence of a drug is of particular importance. so, in this work, the molar conductivities of the ionic liquids, 1-alkyl-3-methylimidazolium bromide, [cnmim]br (n = 4, 6 and 8) in various concentrations of aspirin (asa) in acetonit...

We have used the high nucleophilicity of bromide ion in the form of the ionic liquid, 1-n-butyl-3-methylimidazolium bromide ([bmim][Br]), for the nucleophilic displacement of an alkyl group to regenerate a phenol from the corresponding aryl alkyl ether. Using 2-methoxynaphthalene (1) as a model compound, we found that the combination of ionic liquid [bmim][Br] and p-toluenesulfonic acid with wa...

The conditions of heating, ionic liquid-based ultrasonic-assisted extraction combined with reverse-phase high performance liquid chromatography were optimized to simultaneously isolate and determinate brazilin and protosappanin B in Caesalpinia sappan. Ionic liquids, including [BMIM]Br, [BMIM]BF4, [BMIM]PF6 and [HMIM]PF6, were selected as extraction solvents while methanol, acetone, acetonitril...

the anticoagulant racemic warfarin is synthesized by the michael addition of 4-hydroxycoumarin with benzalacetone in the present of equimolar amounts of imidazolium based ionic liquids [bmim] bf4 and [bmim] br and other reaction solvents such as h2o, pyridine and ammonia in five different tests. also synthesis of a derivative of warfarin (2-methyl-4-phenyl pyrano [3, 2-c] chromen-5(4h)-one) und...

Several ionic liquids were applied as catalysts for the synthesis of cyclic urethanes from amino alcohols and pressurized CO2 in the presence of alkali metal compounds as promoters. A comparative study was made for the catalytic performance using different ionic liquids, substrates, promoters, and pressures. The optimum catalytic system was BMIM-Br promoted by K2CO3, which, for 1-amino-2-propan...

A novel SBA-15-functionalized TEMPO confined ionic liquid [BMIm]Br was found to be a highly efficient and recyclable catalyst system for the transition-metal-free aerobic oxidation of a wide range of structurally diverse alcohols. Thanks to the strong physical confinement of the ionic liquid inside the mesochannels of SBA-15-supported TEMPO, the resulting solid catalyst showed improved selectiv...

A rapid, green and efficient method for the synthesis of 14-aryl-14H-dibenzo[a,j]xanthene derivatives through a one-pot condensation of 2-naphthol with various aromatic aldehydes in the presences of several acidic ionic liquids including [PSMIM]Cl, [BMIM]HSO4, [BMIM]Cl, [BMIM]Br, and [BMIM]BF4 as organocatalysts and task-specific acidic ionic liquids (AILs) under solvent-free conditions is desc...