The disease has four main causes: sebaceous hyperplasia and hyperseborrhoea; hyperkeratinization and consequent keratinocyte accession; colonization of Propionibacterium acnes (P. acnes) and respective Staphylococcus albus and inflammation and immune response. The production of sebum by sebocytes is stimulated by androgens, such as testosterone, which in turn stimulate the production of sebocyt...

This study was aimed to depict potential effects of stable formulation (water in oil emulsion), containing 3% green tea (Camellia sinensis L) extract on skin sebum production in healthy human volunteers. For this purpose formulation was designed using 3% ethanolic green tea extract and Abil®EM90 was used as an emulsifier. Formulation was applied to the cheeks of healthy human volunteers (n=10) ...

The chemical composition of the gland-pad sebum of gerbils of both sexes is analysed using gas-liquid chromatographical and mass spectroscopical techniques and compared with the lipids from distal skin areas. Cholesterol esters, with (omega-1)-methyl-substituted fatty acids as acidic constituents, were shown to occur in the gland-pad sebum of both sexes in high concentrations, whereas cholesta-...

This study was aimed to investigate the effects of cream containing Ficus carica L. fruit (Fig) extract on various skin parameters such as skin melanin, erythema, moisture content, trans-epidermal water loss and sebum. For this purpose, formulation with 4% concentrated extract of F. carica fruit and base without extract were developed. Base served as a control. Both base and formulation were ap...

To investigate androgen effects on the skin pilosebaceous unit, we studied 21 male-to-female transsexuals and 17 female-to-male transsexuals receiving cross-sex hormones. At baseline and after 4, 8, and 12 months, hair growth was evaluated by the Ferriman-Gallwey score; acne by the Leeds classification; hair growth rate, density, and shaft diameter by image analysis; and sebum production by Seb...

The aim of this work was to study skin parameters like melanin, erythema, skin hydration, and sebum score of six body sites namely volar forearm, cheek, chin, forehead, neck and post auricular skin of Asian (Indian) population with different skin colour and types to depict the formulation to be used for taking care. Initially skin colour of various volunteers was assessed by the reference of co...