It has long been known that the serum of certain leprosy patients gives positive reactions with tests for syphilis. These reactions have not been understood and have been interpreted as biologic ‘(false positives.” The reason for this interpretation undoubtedly lies in the widespread assumption that only in syphilis and in closely related diseases, such as yaws and bejel, are serum reactions wi...

Recent observations have detected surface active organics in atmospheric aerosols. We have studied the reaction of N2O5 on aqueous natural seawater and NaCl aerosols as a function of sodium dodecyl sulfate (SDS) concentration to test the effect of varying levels of surfactant on gasaerosol reaction rates. SDS was chosen as a proxy for naturally occurring long chain monocarboxylic acid molecules...

Biphenyl Dimethyl Dicarboxylate (DDB) and Silymarin are widely used drugs for the treatment of hepatitis C virus, have poor bioavailability due to their low aqueous solubility that limits their dissolution rates. To overcome these limitations solid dispersions (SDs) and self-microemulsifing drug delivery systems (SMEDDS) were prepared in an attempt to improve their release profile. SDs were pre...

C4-binding protein (C4-bp), a new component of the complement system, was isolated from human plasma by precipitation with polyethyleneglycol, followed by chromatography on ion exchangers. C4-bp was identified on sodium dodecyl- sulfate polyacrylamide gel electrophoresis (SDS-PAGE) by two independent criteria: its ability to bind to C4b, and immunoprecipitation with a monospecificantiserum. Pur...

A new simple reaction-diffusion system is presented focusing on pattern formation phenomena as consecutive precipitation fronts and distortion of the precipitation front. The chemical system investigated here is based on the amphoteric property of aluminum hydroxide and exhibits two unique phenomena. Both the existence of consecutive precipitation fronts and distortion are reported for the firs...

The Lowry protein assay is widely used to quantify proteins in the laboratory. As the assay is susceptible various interfering substances, the protein test sample is frequently first purified by precipitating the proteins using trichloroacetic acid (TCA). However, TCA precipitates proteins poorly in the presence of sodium dodecyl sulfate (SDS), a detergent very commonly used in biological resea...

Material design at submicron scales would be profoundly affected if the formation of precipitation patterns could be easily controlled. It would allow the direct building of bulk structures, in contrast to traditional techniques which consist of removing material in order to create patterns. Here, we discuss an extension of our recent proposal of using electrical currents to control precipitati...

Starvation of rats for 48 h increased the activity of PDH (pyruvate dehydrogenase) kinase 2.2-fold in extracts of liver mitochondria, 2.9-fold in PDH complex partially purified therefrom by fractional precipitation, and 5-fold in PDH complex partially purified by gel filtration on Sephacryl S-300. A protein fraction was separated from PDH complex in extracts of rat liver mitochondria by gel fil...