INTRODUCTION Sclerosing cholangitis represents an array of chronic, cholestatic diseases of the intrahepatic and extrahepatic bile duct systems. Clinically, this syndrome is characterized by progressive fatigue, pruritus, and in later stages, by abdominal pain, recurrent fever, and jaundice. These symptoms are resultant from inflammatory and fibrosing obstruction of the biliary system. The prog...

Introduction. Sclerosing cholangitis is characterized by an inflammatory and fibrotic lesion of intra- and/or extrahepatic bile ducts. When a causal mechanism of a bile duct lesion is identified, the sclerosing cholangitis is considered secondary. The vasculitis, including the Behçet disease, is cited as a probable cause of the ischemia and the sclerosing cholangitis. No cases of extrahepatic s...

Autoimmune sclerosing cholangitis is an overlap syndrome characterized by features of both autoimmune hepatitis and primary sclerosing cholangitis, the latter usually involving the large bile ducts. Autoimmune sclerosing cholangitis occurs more often in children than in adults and is frequently associated with inflammatory bowel disease, predominantly ulcerative colitis. We report a unique case...

INTRODUCTION Although myasthenia gravis is frequently associated with other disorders, it has not been reported together with primary sclerosing cholangitis, complicating the administration of liver-toxic immunosuppressive therapy. CASE PRESENTATION A 73-year-old Caucasian woman with a history of arterial hypertension, thyroid dysfunction, glaucoma, right-sided ptosis and later generalized we...

BACKGROUND Primary sclerosing cholangitis is a rare chronic cholestatic condition of unknown etiology, frequently associated with inflammatory bowel disease and characterized by diffuse fibrosing and inflammatory destruction of the intra- and/or extrahepatic biliary duct system. PATIENTS AND METHODS The study involved 14 children with primary sclerosing cholangitis confirmed by either liver b...

CONTEXT Autoimmune pancreatitis and sclerosing cholangitis associated with autoimmune pancreatitis respond well to steroid therapy. Some criteria used for the differential diagnosis of autoimmune pancreatitis and sclerosing cholangitis with autoimmune pancreatitis include the response to a steroid trial. CASE REPORT A 68-year-old woman was diagnosed as having type 3 sclerosing cholangitis wit...

The term secondary sclerosing cholangitis (SSC) represents a spectrum of variably progressive cholestatic diseases of the intrahepatic and/or extrahepatic biliary system. Numerous different causes for the development of SSC have been described: toxic, infectious, immunological, ischemic, and chronic obstructive [1, 2]. In our review we will focus only on ‘sclerosing cholangitis in critically il...

Background: One of the most serious late complications, after evacuation of liver hydatid cyst and instillation of scolicidal agents is sclerosing cholangitis, most probably caused by the type of scolicidal agents instilled. Objective:  To determine the incidence of sclerosing cholangitis after intra-biliary tract infusion of 5% saline and 0.5% silver nitrate. Methods: 5% hypertonic saline and ...

A variety of diseases are included under the umbrella term 'cholangitis', including hepatobiliary diseases with an autoimmune pathogenesis (such as primary sclerosing cholangitis, primary biliary cholangitis, and IgG4-associated sclerosing cholangitis) and disease processes associated with intraductal stones and infectious etiologies (such as ascending bacterial cholangitis, recurrent pyogenic ...