A simple neutron counter based on a scintillator strip, a wavelength shifter rod, and a photomultiplier was constructed in order to compare the properties of such a detector to a commercially available He counter. A calculation of the number of photons per absorbed neutron shows that with the bright Li Gd (11BO3)3 scintillator, light levels should be sufficient to perform pulse height discrimin...

The gas proportional scintillation counter/microstrip gas chamber (GPSC/MSGC) hybrid detector for X-ray spectrometry is described. The detector uses a CsI-coated microstrip plate placed in direct contact with the gas-filling as the photosensor readout for the GPSC scintillation substituting for the photomultiplier tube (PMT). Usable photosensor maximum gain is limited by optical positive feedba...

The TopCountTM Microplate Scintillation Counter quantitates radioisotopes by liquid scintillation counting in standard microplate formats. Assays that previously had to be transferred from microplates to vials or to non-standard formats for counting can now be quantitated directly in microplates. TopCount can count up to 12 samples simultaneously with performance comparable to that of discrete ...

A software package for the automation of a Beckman LS9000 liquid scintillation counter is presented. The package provides effective on-line data capture (with a Perkin Elmer 3230 32-bit minicomputer), database management, audit trail and archiving facilities. Key features of the package are rapid andJlexible data entry, background subtraction, half-life correction, ability to queue several samp...

A competitive binding assay for serum thyroxine has been automated, with the use of small, reusable Sephadex columns to separate thyroxine from endogenous thyroid-binding globulin and later to separate the bound and free thyroxine. Sixty samples an hour are run through columns, which are held in an aluminum turntable rotated by a fraction collector motor. Reagents and samples are fed to the col...