Extracorporeal membrane oxygenation has been used successfully to support both cardiac and pulmonary function following Stage I Norwood operation. Determination of the return of native cardiac function and pulmonary function can be easily accomplished because of the single ventricle physiology. The pulmonary function can be assessed while on full flow ECMO by isolating the membrane oxygenator g...

Myocardial mean myoglobin oxygen saturation was determined spectroscopically from isolated guinea pig hearts perfused with red blood cells during increasing hypoxia. These experiments were undertaken to compare intracellular myoglobin oxygen saturation in isolated hearts perfused with a modest concentration of red blood cells (5% hematocrit) with intracellular myoglobin saturation previously re...

This note presents a new approach to deriving stability conditions for continuous-time linear systems interconnected with a saturation. The method presented here can be extended to handle a deadzone, or in general, nonlinearities in the form of piecewise linear functions. By representing the saturation as a constrained optimization problem, the necessary (Kuhn–Tucker) conditions for optimality ...