The root of Panax ginseng C.A. MEYER has been reported to have an anti-stress action. Therefore, the effects of ginseng components on functions of adrenal medulla, which is one of the most important organs responsive to stress, were investigated in vitro. First, the components of ginseng were mainly divided into two fractions, that is, the saponin-rich and non-saponin fractions. The saponin-ric...

background: malignant melanoma is a highly aggressive malignant melanocytic neoplasm which resists against the most conventional therapies. sea cucumber as one of marine organisms contains bioactive compounds such as polysaccharide, terpenoid and other metabolites which have anti-cancer, anti-tumor, anti-inflammatory and antioxidant properties. the present study was designed to investigate the ...

The present study monitored the effect of 2, 10, and 50 mg/L of Panax notoginseng saponin exposure following hypoxia-reoxygenation injury in fetal rat cortical neurons. Results showed that varying doses of Panax notoginseng saponin significantly enhanced the cell viability of neurons, reduced malondialdehyde content, increased superoxide dismutase activity, inhibited mRNA and protein expression...

A total of 3 experiments (Exp), in vitro and in vivo, were conducted to investigate the effects of saponin extracts from Quillaja saponaria (QS), Yucca schidigera (YS) and Camellia sinensis (TS) on CH4 emissions from steers. The in vitro Exp was carried out to determine the effects of saponin inclusion on ruminal methanogenesis and fermentation parameters. Two doses (0.5% and 2.0% of substrate ...

The genus Allium is a rich source of steroidal saponins, and its medicinal properties have been attributed to these bioactive compounds. The saponin compounds with diverse structures play a pivotal role in Allium's defense mechanism. Despite numerous studies on the occurrence and chemical structure of steroidal saponins, their biosynthetic pathway in Allium species is poorly understood. The mon...

Saponins are used in medicine due to their pharmacological and immunological effects. To better understand interactions of saponins with model membranes and natural membranes of, for example, erythrocytes, Langmuir film balance experiments are well established. For most saponins, a strong interaction with cholesterol was demonstrated in dependence of both the aglycone part and the sugar moietie...

Etioplast, Protochlorophyllide, Prolamellar Body, Saponin, Red Light Exposure to red light of high intensities leads to saponin and prolamellar body degradation in etiolated Avena sativa seedlings. Exposure to red light of low intensities increases the saponin percentage found in prolamellar bodies without changing the overall saponin content. Proto­ chlorophyllide is assumed to act a decisive ...

AIM This investigation aimed to assess the hepatoprotective effect of saponin fraction isolated from the fruit pericarp of Sapindus mukorossi on carbon tetrachloride (CCl(4))-induced hepatotoxicity. METHODS Fruit of S. mukorossi was collected and authenticated, and dried pericarp powder subjected to extraction with cold ethanol (70%) by maceration followed by isolation of total saponin fracti...

The aim of the present work was to examine the immunopharmacological (anti-microbial and anti-inflammatory) effect of saponin on human peripheral blood mononuclear cells (PBMC) that are isolated as well as purified from infected (virally) and non-infected (normal) human whole blood samples. However, there is little information available concerning the effect of crude saponin on human PBMC in ca...

This study investigated the effects of garlic oil (0.25 g/L), nitrate (5 mM), and quillaja saponin (0.6 g/L), alone and in binary or ternary combinations, on methanogenesis, rumen fermentation, and abundances of select microbial populations using in vitro rumen cultures. Potential adaptation to these compounds was also examined by repeated transfers of the cultures on alternate days until day 1...